Frizzled Family Receptor 7 (FZD7) Peptide
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- Target See all FZD7 products
- FZD7 (Frizzled Family Receptor 7 (FZD7))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-FZD7 antibody (Catalog #: ARP41251_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- FZD7 (Frizzled Family Receptor 7 (FZD7))
- Synonyms
- FzE3 Peptide, Fz-7 Peptide, Xfz7 Peptide, frizzled-7 Peptide, frizzled7 Peptide, frz-7 Peptide, frz7 Peptide, fz7 Peptide, fzd7-a Peptide, fzd7-b Peptide, fze3 Peptide, Fz7 Peptide, cFz-7 Peptide, fb38g02 Peptide, fc44b09 Peptide, fz13 Peptide, fz7a Peptide, fz7b Peptide, wu:fb38g02 Peptide, wu:fc44b09 Peptide, zg13 Peptide, frizzled class receptor 7 Peptide, frizzled class receptor 7 L homeolog Peptide, frizzled class receptor 7b Peptide, FZD7 Peptide, fzd7.L Peptide, fzd7 Peptide, Fzd7 Peptide, fzd7b Peptide
- Background
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FZD7 is 7-transmembrane domain protein that is receptor for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif.Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas.
Alias Symbols: FzE3
Protein Interaction Partner: DLG1,DLG2,DLG4,MAGI3,UBQLN1,UBQLN4,DLG4,UBQLN1
Protein Size: 574 - Molecular Weight
- 63 kDa
- Gene ID
- 8324
- NCBI Accession
- NM_003507, NP_003498
- UniProt
- O75084
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