Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM) (Middle Region) Peptide
GATM
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all GATM products
- GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-GATM antibody (Catalog #: ARP48553_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GATM (Glycine Amidinotransferase (L-Arginine:glycine Amidinotransferase) (GATM))
- Synonyms
- AT Peptide, AGAT Peptide, CCDS3 Peptide, 1810003P21Rik Peptide, AI314789 Peptide, cb409 Peptide, wu:fa08a06 Peptide, zgc:65855 Peptide, glycine amidinotransferase (L-arginine:glycine amidinotransferase) L homeolog Peptide, glycine amidinotransferase Peptide, glycine amidinotransferase (L-arginine:glycine amidinotransferase) Peptide, gatm.L Peptide, GATM Peptide, Gatm Peptide, gatm Peptide
- Background
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GATM is a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: AGAT, AT
Protein Interaction Partner: GATM
Protein Size: 423 - Molecular Weight
- 44 kDa
- Gene ID
- 2628
- NCBI Accession
- NM_001482, NP_001473
- UniProt
- P50440
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