Glutamate Receptor 1 (GLUR1) (N-Term) Peptide
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- Target See all Glutamate Receptor 1 (GLUR1) products
- Glutamate Receptor 1 (GLUR1)
- Protein Region
- N-Term
- Origin
- Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CGALHVCFIT PSFPVDTSNQ FVLQLRPELQ EALISIIDHY KWQTFVYIYD
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Gria1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Glutamate Receptor 1 (GLUR1)
- Synonyms
- GLUH1 Peptide, GLUR1 Peptide, GLURA Peptide, GluA1 Peptide, HBGR1 Peptide, gluR-A Peptide, 2900051M01Rik Peptide, Glr-1 Peptide, Glr1 Peptide, GluR-A Peptide, GluRA Peptide, Glur-1 Peptide, Glur1 Peptide, HIPA1 Peptide, gluR-K1 Peptide, GRIA1 Peptide, glur1 Peptide, Gria1 Peptide, glur1b Peptide, gria1.2 Peptide, sb:eu293 Peptide, ZfGluR1a Peptide, glur1a Peptide, gria1.1 Peptide, zfGRIA1[a] Peptide, glutamate ionotropic receptor AMPA type subunit 1 Peptide, glutamate receptor, ionotropic, AMPA1 (alpha 1) Peptide, glutamate receptor, ionotropic, AMPA 1 Peptide, glutamate receptor, ionotropic, AMPA 1 L homeolog Peptide, GluR1 protein Peptide, Glutamate receptor 1 Peptide, glutamate receptor, ionotropic, AMPA 1b Peptide, glutamate receptor, ionotropic, AMPA 1a Peptide, GRIA1 Peptide, Gria1 Peptide, gria1 Peptide, gria1.L Peptide, glur1 Peptide, glr-1 Peptide, gria1b Peptide, gria1a Peptide
- Background
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Gria1 is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
Alias Symbols: 2900051M01Rik, AI853806, Glr-1, Glr1, GluR-A, GluRA, Glur-1, Glur1, HIPA1, GluA1, gluR-K1
Protein Size: 907 - Molecular Weight
- 99 kDa
- Gene ID
- 14799
- NCBI Accession
- NM_001113325, NP_001106796
- UniProt
- P23818
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