Homeobox B8 (HOXB8) (N-Term) Peptide
HOXB8
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HOXB8 products
- HOXB8 (Homeobox B8 (HOXB8))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HOXB8 antibody (Catalog #: ARP39583_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HOXB8 (Homeobox B8 (HOXB8))
- Synonyms
- HOX2 Peptide, HOX2D Peptide, Hox-2.4 Peptide, Hox2r1a Peptide, hoxa8 Peptide, z-9 Peptide, HBX Peptide, HBX24 Peptide, HOXB8 Peptide, homeobox B8 Peptide, homeobox protein Hox-B8 Peptide, homeo box B8 Peptide, homeobox B8b Peptide, porcine homeobox Peptide, HOXB8 Peptide, Hoxb8 Peptide, LOC785855 Peptide, hoxb8b Peptide, HOX-2.4 Peptide
- Background
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HOXB8 is a member of the Antp homeobox family and is a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. HOXB8 functions as a sequence-specific transcription factor that is involved in development. Increased expression of this HOXB8 gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania.
Alias Symbols: HOX2, HOX2D, Hox-2.4
Protein Interaction Partner: MEIS1,PBX1,PBX2,PBX3,PBX1,PBX3
Protein Size: 243 - Molecular Weight
- 28 kDa
- Gene ID
- 3218
- NCBI Accession
- NM_024016, NP_076921
- UniProt
- P17481
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