Histidine-Rich Glycoprotein (HRG) (Middle Region) Peptide
-
- Target See all HRG products
- HRG (Histidine-Rich Glycoprotein (HRG))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HRG antibody (Catalog #: ARP41397_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- HRG (Histidine-Rich Glycoprotein (HRG))
- Synonyms
- AI265597 Peptide, AW413091 Peptide, D16jh2 Peptide, D18020 Peptide, Hprg Peptide, Hrgp Peptide, HPRG Peptide, HRGP Peptide, THPH11 Peptide, HRG1 Peptide, histidine rich glycoprotein Peptide, histidine-rich glycoprotein Peptide, HRG Peptide, LOAG_12427 Peptide, LOC100597044 Peptide, Hrg Peptide
- Background
-
This histidine-rich glycoprotein(HRG) contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DKFZp779H1622, HPRG, HRGP
Protein Interaction Partner: C1QA,C1QB,FCGR1A,FGA,PLG,THBS1,FGA
Protein Size: 525 - Molecular Weight
- 58 kDa
- Gene ID
- 3273
- NCBI Accession
- NM_000412, NP_000403
- UniProt
- P04196
-