Serotonin Receptor 2B (HTR2B) (N-Term) Peptide

Details for Product No. ABIN978347, Supplier: Log in to see
Protein Name
  • 5-HT2B
  • 5HT2B
  • 5htr2b
  • HTR2B
  • 5ht2b
  • zgc:194094
  • zgc:194119
  • AJ012488
  • AV377389
  • 5-HT(2B)
  • 5-hydroxytryptamine (serotonin) receptor 2B
  • 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
  • HTR2B
  • htr2b
  • LOC100228803
  • Htr2b
Protein Region
N-Term
Origin
Human
2
Source
Synthetic
Application
Blocking Peptide (BP), Immunocytochemistry (ICC), Western Blotting (WB)
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Blocked Antibody anti-Serotonin Receptor 2B antibody (HTR2B) (N-Term) (ABIN2779377)
Sequence QTESIPEEMK QIVEEQGNKL HWAALLILMV IIPTIGGNTL VILAVSLEKK
Characteristics This is a synthetic peptide designed for use in combination with anti-HTR2B Antibody(ARP30716_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Purification Purified
Background Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.

Alias Symbols: 5-HT(2B), 5-HT2B

Protein Interaction Partner: GNA11,GNAQ

Protein Size: 481
Molecular Weight 54 kDa
Gene ID 3357
NCBI Accession NM_000867, NP_000858
UniProt P41595
Application Notes Each Investigator should determine their own optimal working dilution for specific applications.
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
Concentration 1 mg/mL
Buffer Final peptide concentration is 1 mg/mL in PBS.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.