Serotonin Receptor 2B (HTR2B) (N-Term) Peptide
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- Target See all Serotonin Receptor 2B (HTR2B) products
- Serotonin Receptor 2B (HTR2B)
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunocytochemistry (ICC)
- Sequence
- QTESIPEEMK QIVEEQGNKL HWAALLILMV IIPTIGGNTL VILAVSLEKK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-HTR2B Antibody(ARP30716_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Serotonin Receptor 2B (HTR2B)
- Synonyms
- 5-HT2B Peptide, 5HT2B Peptide, 5htr2b Peptide, HTR2B Peptide, 5ht2b Peptide, zgc:194094 Peptide, zgc:194119 Peptide, AJ012488 Peptide, AV377389 Peptide, 5-HT(2B) Peptide, 5-hydroxytryptamine receptor 2B Peptide, 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled Peptide, 5-hydroxytryptamine (serotonin) receptor 2B Peptide, HTR2B Peptide, htr2b Peptide, Htr2b Peptide
- Background
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Multiple receptor subtypes of serotonin neurotransmitters with multiple physiologic functions have been recognized. The 5-HT-2 receptors mediate many of the central and peripheral physiologic functions of serotonin. Cardiovascular effects include contraction of blood vessels and shape changes in platelets, central nervous system effects include neuronal sensitization to tactile stimuli and mediation of hallucinogenic effects of phenylisopropylamine hallucinogens.
Alias Symbols: 5-HT(2B), 5-HT2B
Protein Interaction Partner: GNA11,GNAQ
Protein Size: 481 - Molecular Weight
- 54 kDa
- Gene ID
- 3357
- NCBI Accession
- NM_000867, NP_000858
- UniProt
- P41595
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