Microtubule-Associated Protein 4 (MAP4) (N-Term) Peptide
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- Target See all MAP4 products
- MAP4 (Microtubule-Associated Protein 4 (MAP4))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LKETERASPI KMDLAPSKDM GPPKENKKET ERASPIKMDL APSKDMGPPK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAP4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAP4 (Microtubule-Associated Protein 4 (MAP4))
- Synonyms
- XMAP4 Peptide, mtap4 Peptide, AA407148 Peptide, MAP-4 Peptide, Mtap-4 Peptide, Mtap4 Peptide, microtubule associated protein 4 Peptide, microtubule associated protein 4 L homeolog Peptide, microtubule-associated protein 4 Peptide, MAP4 Peptide, map4.L Peptide, Map4 Peptide
- Background
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MAP4 is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression.
Alias Symbols: DKFZp779A1753, MGC8617
Protein Interaction Partner: CCNB1,MARK4,TUBB,CCNB1,CDK1,ENO2,MARK1,MARK4,NR1I3,RXRB,RXRG,TUBB,CDK1,ENO2,FYCO1,MARK4
Protein Size: 1152 - Molecular Weight
- 121 kDa
- Gene ID
- 4134
- NCBI Accession
- NM_002375, NP_002366
- UniProt
- P27816
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