Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5) (Middle Region) Peptide
MAP4K5
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MAP4K5 products
- MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MAP4K5 antibody (Catalog #: ARP33101_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAP4K5 (Mitogen-Activated Protein Kinase Kinase Kinase Kinase 5 (MAP4K5))
- Synonyms
- GCKR Peptide, KHS Peptide, KHS1 Peptide, MAPKKKK5 Peptide, 4432415E19Rik Peptide, RGD1562028 Peptide, fl74c10 Peptide, wu:fl74c10 Peptide, zgc:55719 Peptide, zgc:55985 Peptide, mitogen-activated protein kinase kinase kinase kinase 5 Peptide, mitogen-activated protein kinase kinase kinase kinase 5 S homeolog Peptide, MAP4K5 Peptide, Map4k5 Peptide, map4k5 Peptide, map4k5.S Peptide
- Background
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MAP4K5 may play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway.This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.
Alias Symbols: GCKR, KHS, KHS1, MAPKKKK5
Protein Interaction Partner: ABL1,BCR,CRK,CRKL,GRB2,TANK,TRAF2,CRK,CRKL,TRAF2
Protein Size: 846 - Molecular Weight
- 95 kDa
- Gene ID
- 11183
- NCBI Accession
- NM_006575, NP_006566
- UniProt
- Q9Y4K4
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