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Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2) (Middle Region) Peptide

MAPKAPK2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN979806
  • Target See all MAPKAP Kinase 2 (MAPKAPK2) products
    MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    KLTDFGFAKE TTQNALQTPC YTPYYVAPEV LGPEKYDKSC DMWSLGVIMY
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-MAPKAPK2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MAPKAP Kinase 2 (MAPKAPK2) (Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 (MAPKAPK2))
    Synonyms
    mapkapk2 Peptide, wu:fb30e10 Peptide, wu:fc56c10 Peptide, wu:fi03a01 Peptide, MGC78852 Peptide, MAPKAPK2 Peptide, AA960234 Peptide, MAPKAP-K2 Peptide, MK-2 Peptide, MK2 Peptide, Rps6kc1 Peptide, mitogen-activated protein kinase-activated protein kinase 2a Peptide, mitogen-activated protein kinase-activated protein kinase 2 L homeolog Peptide, mitogen-activated protein kinase-activated protein kinase 2 Peptide, MAP kinase-activated protein kinase 2 Peptide, mapkapk2a Peptide, mapkapk2.L Peptide, MAPKAPK2 Peptide, Mapkapk2 Peptide
    Background
    MAPKAPK2 is a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo.

    Alias Symbols: 3PK, MAPKAP3, MK2, MK-2, MAPKAP-K2

    Protein Interaction Partner: HNRNPA0,MDM2,ARPC5,MDM2,YWHAZ,YWHAZ,AKT1,ALOX5,ARPC5,BAG2,CREB1,EEF2K,ETV1,HNRNPA0,HSF1,HSPB1,LSP1,MAPK14,MAPKAPK2,PHC2,SHC1,SRF,TCF3,TH,TSC2,YWHAZ,ZFP36,AKT1,CDC25B,EGF,ETV1,HSPB1,HSPB1,MAPK1,MAPK14,PHC2,SHC1,Tsc2

    Protein Size: 370
    Molecular Weight
    42 kDa
    Gene ID
    9261
    NCBI Accession
    NM_004635, NP_004626
    UniProt
    Q16644
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