Afadin (MLLT4) Peptide
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- Target See all Afadin (MLLT4) products
- Afadin (MLLT4)
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MLLT4 antibody (Catalog #: ARP34225_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- Afadin (MLLT4)
- Synonyms
- MLLT4 Peptide, af-6 Peptide, af6 Peptide, si:ch211-278j12.1 Peptide, AF6 Peptide, RP3-431P23.3 Peptide, 5033403D15Rik Peptide, Af-6 Peptide, Afadin Peptide, Gm314 Peptide, I-afadin Peptide, S-afadin Peptide, Af6 Peptide, afadin, adherens junction formation factor Peptide, afadin, adherens junction formation factor L homeolog Peptide, afadin, adherens junction formation factor a Peptide, afadin Peptide, AFDN Peptide, afdn.L Peptide, afdna Peptide, LOC589923 Peptide, LOC100177180 Peptide, afdn Peptide, Afdn Peptide
- Background
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AF6 is a Ras target that regulates cell-cell adhesions downstream of Ras activation. It is fused with MLL in leukemias caused by t(6,11) translocations.
Alias Symbols: RP3-470B24.4, AF-6, AF6, AFADIN, FLJ34371, RP3-431P23.3
Protein Interaction Partner: EPHA7,EPHB2,EPHB3,EPHB6,BCR,CTNNA1,EPHA7,EPHB2,EPHB3,EPHB6,F11R,HRAS,JAG1,LMO2,MRAS,NRXN2,NRXN3,PFN1,PICK1,PVRL1,PVRL2,PVRL3,PVRL4,RALGDS,RAP1A,RAP1GAP,RAP2A,RIT1,RIT2,RRAS,RRAS2,SMAD2,SORBS1,SORBS2,SSX2IP,TJP1,USP9X,YWHAB,YWHAG,BCR,CTNNA1,EPHA7,EPHB2,EPHB3,EPHB6,F11R,HRAS,JAG1,LMO2,Mras,NRAS,NRXN1,NRXN2,NRXN3,PFN1,PVRL1,PVRL2,PVRL3,RAP1A,RAP1GAP,RIN1,RIT1,RRAS2,SORBS1,SORBS2,SSX2IP,TJP1,USP9X,YWHAB,YWHAG,YWHAQ,cgn
Protein Size: 674 - Molecular Weight
- 74 kDa
- Gene ID
- 4301
- NCBI Accession
- NM_001040000
- UniProt
- P55196
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