Ornithine Decarboxylase Antizyme 3 (OAZ3) (Middle Region) Peptide
OAZ3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all OAZ3 products
- OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DRRLFLDIPY QALDQGNRES LTATLEYVEE KTNVDSVFVN FQNDRNDRGA
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-OAZ3 Antibody(ARP53713_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- OAZ3 (Ornithine Decarboxylase Antizyme 3 (OAZ3))
- Synonyms
- Az3 Peptide, Oaz-t Peptide, AZ3 Peptide, OAZ-t Peptide, TISP15 Peptide, Az-3 Peptide, ornithine decarboxylase antizyme 3 Peptide, OAZ3 Peptide, Oaz3 Peptide
- Background
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Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: AZ3, OAZ-t, TISP15
Protein Interaction Partner: GGN,OAZ1,SMAD1
Protein Size: 187 - Molecular Weight
- 21 kDa
- Gene ID
- 51686
- NCBI Accession
- NM_016178, NP_057262
- UniProt
- Q9UMX2
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