Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1) (Middle Region) Peptide
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- Target See all PABP (PABPC1) products
- PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PABPC1 antibody (Catalog #: ARP40403_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PABP (PABPC1) (Poly(A) Binding Protein, Cytoplasmic 1 (PABPC1))
- Synonyms
- PAB1 Peptide, PABP Peptide, PABP1 Peptide, PABPC2 Peptide, PABPL1 Peptide, Pabp1 Peptide, PabpI Peptide, Pabpl1 Peptide, ePAB Peptide, Pabp Peptide, pab1 Peptide, pabp Peptide, pabp1 Peptide, pabpc1 Peptide, pabpc2 Peptide, PABPC1 Peptide, wu:fb16a02 Peptide, wu:fi19b08 Peptide, wu:fj12d09 Peptide, wu:fj61f06 Peptide, zgc:109879 Peptide, zgc:77608 Peptide, poly(A) binding protein cytoplasmic 1 Peptide, poly(A) binding protein, cytoplasmic 1 Peptide, poly(A) binding protein, cytoplasmic 1 S homeolog Peptide, poly(A) binding protein cytoplasmic 1 like Peptide, poly(A) binding protein, cytoplasmic 1 L homeolog Peptide, poly(A) binding protein, cytoplasmic 1a Peptide, poly A binding protein, cytoplasmic 1 b Peptide, PABPC1 Peptide, Pabpc1 Peptide, pabpc1.S Peptide, pabpc1 Peptide, PABPC1L Peptide, pabpc1.L Peptide, pabpc1a Peptide, pabpc1b Peptide
- Background
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The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4, MIM 603407), and PABP3 (PABPC3, MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.The poly(A)-binding protein (PABP), which is found complexed to the 3-prime poly(A) tail of eukaryotic mRNA, is required for poly(A) shortening and translation initiation. In humans, the PABPs comprise a small nuclear isoform and a conserved gene family that displays at least 3 functional proteins: PABP1 (PABPC1), inducible PABP (iPABP, or PABPC4, MIM 603407), and PABP3 (PABPC3, MIM 604680). In addition, there are at least 4 pseudogenes, PABPCP1 to PABPCP4.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: PAB1, PABP, PABP1, PABPC2, PABPL1
Protein Interaction Partner: ANAPC5,ATXN2,CARM1,CSDE1,EIF4B,EIF4G1,EIF4G3,GNB2L1,GSPT1,GSPT2,HNRNPD,NDRG1,PABPC1,PAIP1,PAIP2,PAIP2B,PAN2,PCBP1,PCBP2,PCSK7,PXN,SFRS12,STAU1,SYCP3,SYNCRIP,YWHAG,AIRE,ANAPC5,BCAR3,CNOT7,DYNLL1,EIF4A1,EIF4A2,EIF4B,EIF4G1,EIF4G3,ETF1,GNB2L1,GSPT1,GSPT2,HNRNPA1,IKBKE,PAIP1,PAIP2,PAN2,PAN3,PINX1,PUF60,PXN,TOB1,UPF1
Protein Size: 636 - Molecular Weight
- 71 kDa
- Gene ID
- 26986
- NCBI Accession
- NM_002568, NP_002559
- UniProt
- P11940
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