Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B) Peptide
POLR3B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all POLR3B products
- POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-POLR3B antibody (Catalog #: ARP48821_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- POLR3B (Polymerase (RNA) III (DNA Directed) Polypeptide B (POLR3B))
- Synonyms
- RGD1565311 Peptide, C128 Peptide, HLD8 Peptide, RPC2 Peptide, 2700078H01Rik Peptide, A330032P03Rik Peptide, C85372 Peptide, RNA polymerase III subunit B Peptide, polymerase (RNA) III (DNA directed) polypeptide B Peptide, Polr3b Peptide, POLR3B Peptide
- Background
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POLR3B belongs to the RNA polymerase beta chain family. DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. POLR3B is the second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. It is proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft.
Alias Symbols: FLJ10388, RPC2, C128, HLD8
Protein Interaction Partner: GPN1,POLR3D,POLR3H,RAE1,RPAP1,RPAP2
Protein Size: 1133 - Molecular Weight
- 128 kDa
- Gene ID
- 55703
- NCBI Accession
- NM_018082, NP_060552
- UniProt
- Q9NW08
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