POU Class 3 Homeobox 3 (POU3F3) (N-Term) Peptide
POU3F3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all POU3F3 products
- POU3F3 (POU Class 3 Homeobox 3 (POU3F3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-POU3F3 antibody (Catalog #: ARP33062_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- POU3F3 (POU Class 3 Homeobox 3 (POU3F3))
- Synonyms
- BRN1 Peptide, OTF8 Peptide, Brn1 Peptide, RHS1 Peptide, Brn-1 Peptide, Otf8 Peptide, Skin1 Peptide, brn1 Peptide, nrl-20 Peptide, nrl20-A Peptide, pou1 Peptide, pou23 Peptide, wu:fb92g06 Peptide, zfpou1 Peptide, zp23 Peptide, zp23pou Peptide, BRN-1.1 Peptide, ZP12POU Peptide, brn1.1 Peptide, pou12 Peptide, wu:fc33a11 Peptide, zp12 Peptide, POU class 3 homeobox 3 Peptide, POU domain, class 3, transcription factor 3 Peptide, POU class 3 homeobox 3 S homeolog Peptide, POU class 3 homeobox 3b Peptide, POU class 3 homeobox 3a Peptide, POU3F3 Peptide, Pou3f3 Peptide, pou3f3.S Peptide, pou3f3b Peptide, pou3f3a Peptide
- Background
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POU3F3 is the transcription factor that acts synergistically with SOX11 and SOX4. POU3F3 plays a role in neuronal development. POU3F3 is implicated in an enhancer activity at the embryonic met-mesencephalic junction, the enhancer element contains the octamer motif (5'-ATTTGCAT-3').POU3F3 is a member of the class III POU family of transcription factors (see POU3F1, MIM 602479) that are expressed in the central nervous system. The POU domain in these proteins is required for high affinity binding to octamer DNA sequences Sumiyama et al. (1996) [PubMed 8703082].[supplied by OMIM].
Alias Symbols: BRN1, OTF8
Protein Interaction Partner: POU3F4,PPP1R15A,SOX10,SOX11,SOX8,POU3F4
Protein Size: 500 - Molecular Weight
- 50 kDa
- Gene ID
- 5455
- NCBI Accession
- NM_006236, NP_006227
- UniProt
- P20264
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