Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1) (Middle Region) Peptide
PSMB1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PSMB1 products
- PSMB1 (Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSMB1 antibody (Catalog #: ARP56460_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PSMB1 (Proteasome (Prosome, Macropain) Subunit, beta Type, 1 (PSMB1))
- Synonyms
- DDBDRAFT_0217063 Peptide, DDBDRAFT_0232957 Peptide, DDB_0217063 Peptide, DDB_0232957 Peptide, AA409053 Peptide, C81484 Peptide, Lmpc5 Peptide, HC5 Peptide, PMSB1 Peptide, PSC5 Peptide, wu:fc51f06 Peptide, zgc:103665 Peptide, proteasome subunit beta 1 Peptide, 20S proteasome subunit beta-1 Peptide, proteasome subunit beta type 1 Peptide, proteasome (prosome, macropain) subunit, beta type 1 Peptide, proteasome subunit beta 1 S homeolog Peptide, psmb1 Peptide, PSMB1 Peptide, psmB1 Peptide, LOC100286342 Peptide, Psmb1 Peptide, psmb1.S Peptide
- Background
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The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMB1 is a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ25321, HC5, KIAA1838, PMSB1, PSC5
Protein Interaction Partner: tat,DCP2,EXOSC6,PLK1,POMP,PSMB3,PSMB5,PSMB7,SERPINB2,CASP4,DCP2,DSTYK,EXOSC6,FANCG,GIYD2,PASK,PLK1,RIOK3,VHL
Protein Size: 241 - Molecular Weight
- 26 kDa
- Gene ID
- 5689
- NCBI Accession
- NM_002793, NP_002784
- UniProt
- P20618
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