Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1) (N-Term) Peptide
PSTPIP1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PSTPIP1 products
- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- HIQLALTLRE ELRSLEEFRE RQKEQRKKYE AVMDRVQKSK LSLYKKAMES
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PSTPIP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PSTPIP1 (Proline-serine-threonine Phosphatase Interacting Protein 1 (PSTPIP1))
- Synonyms
- cd2bp1 Peptide, cd2bp1l Peptide, cd2bp1s Peptide, h-pip Peptide, papas Peptide, pstpip Peptide, PSTPIP1 Peptide, CD2BP1 Peptide, CD2BP1L Peptide, CD2BP1S Peptide, H-PIP Peptide, PAPAS Peptide, PSTPIP Peptide, def-2 Peptide, proline-serine-threonine phosphatase interacting protein 1 Peptide, proline-serine-threonine phosphatase interacting protein 1 S homeolog Peptide, proline-serine-threonine phosphatase-interacting protein 1 Peptide, PSTPIP1 Peptide, pstpip1.S Peptide, pstpip1 Peptide, Pstpip1 Peptide
- Background
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The protein encoded by this gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome.
Alias Symbols: CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP
Protein Size: 416 - Molecular Weight
- 47 kDa
- Gene ID
- 9051
- NCBI Accession
- NM_003978, NP_003969
- UniProt
- O43586
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