REX4, RNA Exonuclease 4 Homolog (REXO4) Peptide
REXO4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all REXO4 products
- REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-REXO4 antibody (Catalog #: ARP32934_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- REXO4 (REX4, RNA Exonuclease 4 Homolog (REXO4))
- Synonyms
- REXO4 Peptide, REX4 Peptide, XPMC2 Peptide, XPMC2H Peptide, Gm111 Peptide, Xpmc2h Peptide, xpmc2 Peptide, im:7156740 Peptide, si:ch73-209e20.4 Peptide, REX4 homolog, 3'-5' exonuclease Peptide, REX4, 3'-5' exonuclease Peptide, RNA exonuclease 4 Peptide, putative 3'-5' exonuclease Peptide, REXO4 Peptide, Rexo4 Peptide, LOC100229203 Peptide, rexo4.S Peptide, CAALFM_C112440WA Peptide, rexo4 Peptide
- Background
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The regulation of the quinone reductase (QR) gene as well as other genes involved in detoxification is known to be mediated by an electrophile response element (EpRE). QR gene regulation by the antiestrogen-occupied estrogen receptor (ER) is mediated by the EpRE-containing region of the human QR gene, and the ER is one of the complex of proteins that binds to the EpRE. REXO4 directly binds to the EpRE and interacts with the ER. The activation of QR gene activity by REXO4 is enhanced in the presence of ER beta.
Alias Symbols: XPMC2, XPMC2H, REX4
Protein Interaction Partner: ESR1,ESR2,ESR1,ESR2
Protein Size: 422 - Molecular Weight
- 47 kDa
- Gene ID
- 57109
- NCBI Accession
- NM_020385, NP_065118
- UniProt
- Q9GZR2
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