Retinal G Protein Coupled Receptor (RGR) (C-Term) Peptide
RGR
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RGR products
- RGR (Retinal G Protein Coupled Receptor (RGR))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GKSGHLQVPA LIAKMVPTIN AINYALGNEM VCRGIWQCLS PQKREKDRTK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RGR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RGR (Retinal G Protein Coupled Receptor (RGR))
- Synonyms
- RP44 Peptide, MGC84794 Peptide, RGR Peptide, rgr Peptide, zgc:110660 Peptide, rgr2 Peptide, wu:fb64c10 Peptide, zgc:109930 Peptide, retinal G protein coupled receptor Peptide, retinal G protein coupled receptor L homeolog Peptide, retinal G protein coupled receptor a Peptide, retinal G protein coupled receptor b Peptide, RGR Peptide, Rgr Peptide, rgr.L Peptide, rgr Peptide, rgra Peptide, rgrb Peptide
- Background
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This gene encodes a putative retinal G-protein coupled receptor. The gene is a member of the opsin subfamily of the 7 transmembrane, G-protein coupled receptor 1 family. Like other opsins which bind retinaldehyde, it contains a conserved lysine residue in the seventh transmembrane domain. The protein acts as a photoisomerase to catalyze the conversion of all-trans-retinal to 11-cis-retinal. The reverse isomerization occurs with rhodopsin in retinal photoreceptor cells. The protein is exclusively expressed in tissue adjacent to retinal photoreceptor cells, the retinal pigment epithelium and Mueller cells. This gene may be associated with autosomal recessive and autosomal dominant retinitis pigmentosa (arRP and adRP, respectively).
Alias Symbols: RP44
Protein Interaction Partner: KIAA1279,RDH5,KIAA1279
Protein Size: 253 - Molecular Weight
- 28 kDa
- Gene ID
- 5995
- NCBI Accession
- NM_001012722, NP_001012740
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