Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2) (Middle Region) Peptide
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- Target See all RPS6KA2 products
- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RPS6KA2 antibody (Catalog #: ARP56170_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RPS6KA2 (Ribosomal Protein S6 Kinase, 90kDa, Polypeptide 2 (RPS6KA2))
- Synonyms
- HU-2 Peptide, MAPKAPK1C Peptide, RSK Peptide, RSK3 Peptide, S6K-alpha Peptide, S6K-alpha2 Peptide, p90-RSK3 Peptide, pp90RSK3 Peptide, 90kDa Peptide, D17Wsu134e Peptide, Rps6ka-rs1 Peptide, Rsk3 Peptide, p90rsk Peptide, pp90rsk Peptide, ribosomal protein S6 kinase A2 Peptide, ribosomal protein S6 kinase, polypeptide 2 Peptide, Rps6ka2 Peptide, RPS6KA2 Peptide
- Background
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RPS6KA2 is a serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Alias Symbols: HU-2, MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, pp90RSK3
Protein Interaction Partner: MAPK1,BAD,CREB1,L1CAM,MAGI1,MAP2K1,MAPK1,MAPK3,RPS6KA2,SHANK1,CREBBP,FOS,JUN,MAPK1,MAPK3,MAPK3,RPS6KA2
Protein Size: 733 - Molecular Weight
- 81 kDa
- Gene ID
- 6196
- NCBI Accession
- NM_021135, NP_066958
- UniProt
- Q15349
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