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Pre-mRNA Branch Site Protein p14 (SF3B14) (N-Term) Peptide

SF3B14 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN983623
  • Target See all Pre-mRNA Branch Site Protein p14 (SF3B14) products
    Pre-mRNA Branch Site Protein p14 (SF3B14)
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-SF3B14 antibody (Catalog #: ARP40828_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    Pre-mRNA Branch Site Protein p14 (SF3B14)
    Synonyms
    6030419K15Rik Peptide, AV001342 Peptide, Sf3b14 Peptide, zgc:86708 Peptide, HSPC175 Peptide, Ht006 Peptide, P14 Peptide, SAP14 Peptide, SF3B14a Peptide, splicing factor 3B, subunit 6 Peptide, splicing factor 3b, subunit 6 Peptide, splicing factor 3b subunit 6 S homeolog Peptide, splicing factor 3b subunit 6 Peptide, Sf3b6 Peptide, sf3b6 Peptide, sf3b6.S Peptide, SF3B6 Peptide
    Background
    SF3B14 is a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. SF3B14 also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site. This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.

    Alias Symbols: CGI-110, HSPC175, Ht006, P14, SAP14, SF3B14a

    Protein Interaction Partner: SF3B1,SF3B1,SF3B14,SF3A2,SF3B1

    Protein Size: 125
    Molecular Weight
    14 kDa
    Gene ID
    51639
    NCBI Accession
    NM_016047, NP_057131
    UniProt
    Q9Y3B4
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