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Sirtuin 4 (SIRT4) (N-Term) Peptide

SIRT4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN983768
  • Target See all SIRT4 products
    SIRT4 (Sirtuin 4 (SIRT4))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-SIRT4 antibody (Catalog #: ARP32452_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    SIRT4 (Sirtuin 4 (SIRT4))
    Synonyms
    SIRT4 Peptide, im:7139453 Peptide, SIR2L4 Peptide, 4930596O17Rik Peptide, sirtuin 4 Peptide, SIRT4 Peptide, sirt4 Peptide, Sirt4 Peptide
    Background
    SIRT4 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. SIRT4 is included in class IV of the sirtuin family. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family.

    Alias Symbols: MGC130046, MGC130047, MGC57437, SIR2L4, sirtuin 4

    Protein Size: 314
    Molecular Weight
    35 kDa
    Gene ID
    23409
    NCBI Accession
    NM_012240, NP_036372
    UniProt
    Q9Y6E7
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