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SIRT4 Products

(Sirtuin 4 (SIRT4))

Categories

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq, Jul 2008].

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Featured SIRT4 Categories

SIRT4 Antibodies

High quality antibodies with extensive validation data.

SIRT4 ELISA Kits

Reliable ELISA kits for a wide range of species.

SIRT4 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended SIRT4 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
Application IHC, WB
Validations
  • (6)
Cat. No. ABIN2779654
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse, Rat
Application ELISA, IHC (p), WB
Validations
  • (2)
  • (4)
Cat. No. ABIN872709
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, ELISA, WB
Validations
  • (1)
  • (4)
Cat. No. ABIN185191
Quantity 100 μg
Datasheet Datasheet

Recommended SIRT4 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6959494
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5593051
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN434857
Quantity 96 tests
Datasheet Datasheet

Recommended SIRT4 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3095481
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
Cat. No. ABIN3136642
Quantity 1 mg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1320048
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our SIRT4 products

Barrea, Tarantino, Somma, Muscogiuri, Macchia, Falco, Colao, Savastano: "Adherence to the Mediterranean Diet and Circulating Levels of Sirtuin 4 in Obese Patients: A Novel Association." in: Oxidative medicine and cellular longevity, Vol. 2017, pp. 6101254, (2018) (PubMed).

Sarikhani, Mishra, Maity, Kotyada, Wolfgeher, Gupta, Singh, Sundaresan: "SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation." in: eLife, Vol. 7, (2018) (PubMed).

Yuan, He, Cheng, Bai, da Silva, Aguiar, Gao: "Tenovin-6 inhibits proliferation and survival of diffuse large B-cell lymphoma cells by blocking autophagy." in: Oncotarget, Vol. 8, Issue 9, pp. 14912-14924, (2017) (PubMed).

Lang, Grether-Beck, Singh, Kuck, Jakob, Kefalas, Altinoluk-Hambüchen, Graffmann, Schneider, Lindecke, Brenden, Felsner, Ezzahoini, Marini, Weinhold, Vierkötter, Tigges, Schmidt, Stühler, Köhrer et al.: "MicroRNA-15b regulates mitochondrial ROS production and the senescence-associated secretory phenotype through sirtuin 4/SIRT4. ..." in: Aging, Vol. 8, Issue 3, pp. 484-505, (2016) (PubMed).

Savastano, Di Somma, Colao, Barrea, Orio, Finelli, Pasanisi, Contaldo, Tarantino: "Preliminary data on the relationship between circulating levels of Sirtuin 4, anthropometric and metabolic parameters in obese subjects according to growth hormone/insulin-like growth factor-1 status." in: Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society, Vol. 25, Issue 1, pp. 28-33, (2015) (PubMed).

Takumida, Takumida, Katagiri, Anniko: "Localization of sirtuins (SIRT1-7) in the aged mouse inner ear." in: Acta oto-laryngologica, pp. 1-12, (2015) (PubMed).

Ott, Plitzko, Krischkowski, Reichmann, Bittner, Mendel, Kunze, Clement, Havemeyer: "Reduction of sulfamethoxazole hydroxylamine (SMX-HA) by the mitochondrial amidoxime reducing component (mARC)." in: Chemical research in toxicology, Vol. 27, Issue 10, pp. 1687-95, (2015) (PubMed).

Takumida, Takumida, Anniko: "Localization of sirtuins in the mouse inner ear." in: Acta oto-laryngologica, Vol. 134, Issue 4, pp. 331-8, (2014) (PubMed).

Benavente, Schnell, Jacobson: "Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin." in: PLoS ONE, Vol. 7, Issue 7, pp. e42276, (2012) (PubMed).

do Amaral, Ueno, Oliveira, Borsonello, Vanzela, Ribeiro, Alves, Barbosa, Carneiro, Boschero: "Reduced expression of SIRT1 is associated with diminished glucose-induced insulin secretion in islets from calorie-restricted rats." in: The Journal of nutritional biochemistry, Vol. 22, Issue 6, pp. 554-9, (2011) (PubMed).

Synonyms and alternative names related to SIRT4

sirtuin 4 (SIRT4), sirtuin 4 (sirt4), sirtuin 4 (Sirt4), 4930596O17Rik, im:7139453, SIR2L4, SIRT4

Protein level used designations for SIRT4

  • sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae)
  • sirtuin 4
  • NAD-dependent ADP-ribosyltransferase sirtuin-4
  • NAD-dependent protein deacetylase sirtuin-4
  • SIR2-like protein 4
  • regulatory protein SIR2 homolog 4
  • sir2-like 4
  • sirtuin type 4
  • NAD-dependent deacetylase sirtuin-4
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