Syntaxin Binding Protein 4 (STXBP4) (N-Term) Peptide
STXBP4
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all STXBP4 products
- STXBP4 (Syntaxin Binding Protein 4 (STXBP4))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- SVNKESMIGV SFEEAKSIIT GAKLRLESAW EIAFIRQKSD NIQPENLSCT
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-STXBP4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- STXBP4 (Syntaxin Binding Protein 4 (STXBP4))
- Synonyms
- STXBP4 Peptide, LOC733742 Peptide, MGC131203 Peptide, DKFZp468L076 Peptide, Synip Peptide, 6030470M02Rik Peptide, syntaxin binding protein 4 Peptide, syntaxin binding protein 4 L homeolog Peptide, STXBP4 Peptide, stxbp4 Peptide, stxbp4.L Peptide, Stxbp4 Peptide
- Background
-
STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
Alias Symbols: FLJ16496, MGC149829, MGC50337, Synip
Protein Size: 553 - Molecular Weight
- 62 kDa
- Gene ID
- 252983
- NCBI Accession
- NM_178509, NP_848604
- UniProt
- Q6ZWJ1
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