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Syntaxin Binding Protein 4 (STXBP4) (N-Term) Peptide

STXBP4 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN984601
  • Target See all STXBP4 products
    STXBP4 (Syntaxin Binding Protein 4 (STXBP4))
    Protein Region
    N-Term
    Origin
    Human
    Source
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    SVNKESMIGV SFEEAKSIIT GAKLRLESAW EIAFIRQKSD NIQPENLSCT
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-STXBP4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    STXBP4 (Syntaxin Binding Protein 4 (STXBP4))
    Synonyms
    STXBP4 Peptide, LOC733742 Peptide, MGC131203 Peptide, DKFZp468L076 Peptide, Synip Peptide, 6030470M02Rik Peptide, syntaxin binding protein 4 Peptide, syntaxin binding protein 4 L homeolog Peptide, STXBP4 Peptide, stxbp4 Peptide, stxbp4.L Peptide, Stxbp4 Peptide
    Background
    STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.

    Alias Symbols: FLJ16496, MGC149829, MGC50337, Synip

    Protein Size: 553
    Molecular Weight
    62 kDa
    Gene ID
    252983
    NCBI Accession
    NM_178509, NP_848604
    UniProt
    Q6ZWJ1
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