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Thymus High Mobility Group Box Protein (TOX) Peptide

TOX Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN985381
  • Target See all TOX products
    TOX (Thymus High Mobility Group Box Protein (TOX))
    Origin
    Human
    Source
    • 2
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-TOX antibody (Catalog #: ARP33702_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    TOX (Thymus High Mobility Group Box Protein (TOX))
    Synonyms
    TOX1 Peptide, 1700007F02Rik Peptide, thymocyte selection associated high mobility group box Peptide, thymocyte selection-associated high mobility group box Peptide, TOX Peptide, Tox Peptide
    Background
    Some high-mobility group (HMG) box proteins (e.g., LEF1) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.Some high-mobility group (HMG) box proteins (e.g., LEF1, MIM 153245) contain a single HMG box motif and bind DNA in a sequence-specific manner, while other members of this family (e.g., HMG1, MIM 163905) have multiple HMG boxes and bind DNA in a sequence-independent but structure-dependent manner. All HMG box proteins are able to induce a sharp bend in DNA. TOX contains a single HMG box motif.[supplied by OMIM].

    Alias Symbols: KIAA0808, TOX1

    Protein Size: 526
    Molecular Weight
    58 kDa
    Gene ID
    9760
    NCBI Accession
    NM_014729, NP_055544
    UniProt
    O94900
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