Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (Middle Region) Peptide
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- Target See all WNT5A products
- WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-WNT5A antibody (Catalog #: ARP32128_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))
- Synonyms
- hWNT5A Peptide, wnt-5A Peptide, wnt5a-B Peptide, WNT5A Peptide, 8030457G12Rik Peptide, Wnt-5a Peptide, Wnt family member 5A Peptide, Wnt family member 5A S homeolog Peptide, wingless-type MMTV integration site family, member 5a Peptide, wingless-type MMTV integration site family, member 5A Peptide, wingless-related MMTV integration site 5A Peptide, Wnt signaling ligand Peptide, WNT5A Peptide, Wnt5a Peptide, wnt5a.S Peptide, wnt5a Peptide, LOC578814 Peptide, wnt5 Peptide
- Background
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The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT5A is a member of the WNT protein family. It shows 98 % , 98 % and 87 % amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction.The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 98 %, 98 % and 87 % amino acid identity to the mouse, rat and the xenopus Wnt5A protein, respectively. The experiments performed in Xenopus laevis embryos identified that human frizzled-5 (hFz5) is the receptor for the Wnt5A ligand and the Wnt5A/hFz5 signaling mediates axis induction. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: hWNT5A
Protein Interaction Partner: FZD1,FZD5,ROR2,FZD1
Protein Size: 380 - Molecular Weight
- 42 kDa
- Gene ID
- 7474
- NCBI Accession
- NM_003392, NP_003383
- UniProt
- P41221
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