Yes-Associated Protein 1 (YAP1) (C-Term) Peptide
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- Target See all YAP1 products
- YAP1 (Yes-Associated Protein 1 (YAP1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LNSGTYHSRD ESTDSGLSMS SYSVPRTPDD FLNSVDEMDT GDTINQSTLP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-YAP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- YAP1 (Yes-Associated Protein 1 (YAP1))
- Synonyms
- YAP Peptide, YAP2 Peptide, YAP65 Peptide, YKI Peptide, xyap Peptide, yap Peptide, yap2 Peptide, yap65 Peptide, yki Peptide, AI325207 Peptide, Yap Peptide, Yap65 Peptide, Yki Peptide, Yorkie Peptide, cb194 Peptide, sb:cb194 Peptide, si:ch211-181p1.5 Peptide, si:dkey-3b8.3 Peptide, wu:fc18c04 Peptide, zgc:158380 Peptide, Yes associated protein 1 Peptide, Yes associated protein 1 S homeolog Peptide, yes-associated protein 1 Peptide, Yes-associated protein 1 Peptide, YAP1 Peptide, yap1.S Peptide, Yap1 Peptide, yap1 Peptide
- Background
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This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alias Symbols: YAP1,YAP65,
Protein Size: 504 - Molecular Weight
- 54 kDa
- Gene ID
- 10413
- UniProt
- P46937
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