ZIC2 (ZIC2) Peptide
ZIC2
Reactivity: Human
Host: Synthetic
BP, IHC, WB
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- Target See all ZIC2 products
- ZIC2
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ZIC2 antibody (Catalog #: ARP35821_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ZIC2
- Synonyms
- HPE5 Peptide, Ku Peptide, cb851 Peptide, fb26a03 Peptide, wu:fb26a03 Peptide, zic2 Peptide, zic2.1 Peptide, hpe5 Peptide, hm:zeh0655 Peptide, id:ibd5017 Peptide, zic2.2 Peptide, zic2l Peptide, Zic family member 2 Peptide, zinc finger protein of the cerebellum 2 Peptide, zic family member 2 (odd-paired homolog, Drosophila), a Peptide, Zic family member 2 L homeolog Peptide, zic family member 2 (odd-paired homolog, Drosophila) b Peptide, ZIC2 Peptide, Zic2 Peptide, zic2a Peptide, zic2.L Peptide, zic2b Peptide
- Background
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ZIC2 is a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects.This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.
Alias Symbols: HPE5
Protein Interaction Partner: GLI1,GLI2,GLI3,GLI1,GLI2,GLI3,RNF180,UBC
Protein Size: 532 - Molecular Weight
- 55 kDa
- Gene ID
- 7546
- NCBI Accession
- NM_007129, NP_009060
- UniProt
- O95409
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