anti-Mouse (Murine) BIM antibody for Immunohistochemistry (Frozen Sections)

Recommended BIM Antibody (supplied by: Log in to see )

Antigen
BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) Antibodies
  • bim
  • BAM
  • BIM
  • BOD
  • 1500006F24Rik
  • Bim
  • Bod
  • BimL
  • BIMEL
  • BCL2-like 11
  • BCL2-like 11 (apoptosis facilitator)
  • bcl2l11
  • LOC100345483
  • BCL2L11
  • Bcl2l11
Reactivity
Human, Mouse (Murine), Rat (Rattus)
333
235
207
9
6
6
4
3
3
1
1
Host
Rabbit
284
29
16
9
7
Clonality
Polyclonal
Conjugate
This BIM antibody is un-conjugated
16
14
11
9
9
9
5
4
4
4
4
4
4
4
4
4
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
279
139
115
80
72
47
33
28
17
7
5
4
3
2
2
2
1
Supplier
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Catalog No. ABIN5551320
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN187549 FACS IHC (fro) IHC (p) IP WB Rat IgG2a Log in to see 14A8

General

Antigen BCL2-Like 11 (Apoptosis Facilitator) (BCL2L11) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(333), (235), (207), (9), (6), (6), (4), (3), (3), (1), (1)
Host Rabbit
(284), (29), (16), (9), (7)
Clonality
Polyclonal
Conjugate This BIM antibody is un-conjugated
(16), (14), (11), (9), (9), (9), (5), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
(279), (139), (115), (80), (72), (47), (33), (28), (17), (7), (5), (4), (3), (2), (2), (2), (1)
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Product Details anti-BIM Antibody

Target Details BIM Application Details Handling Images
Specificity Detects a 23 kDa protein corresponding to the molecular mass of Bim on SDS PAGE immunoblots.
Purification Affinity Chromatography
Immunogen Internal central amino acids of Human Bim
Isotype IgG

Target Details BIM

Product Details anti-BIM Antibody Application Details Handling Images back to top
Antigen
Alternative Name Bcl-2-Like 11 (BCL2L11 Antibody Abstract)
Background Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bim/BOD is a group of three splice variants, BimEL, BimL and BimS, with apparent molecular masses of ~23, 16, and 13 kDa, respectively. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bim or BOD in human, mouse and rat (1,2). Bim/BOD interacts with diverse members in the pro-survival Bcl-2 sub-family including Bcl-2, Bcl-xL and Bcl-w. Bim/BOD induces apoptosis. The messenger RNA of Bim is ubiquitously expressed in multiple tissues and cell lines (1,2).Synonyms: BCL2L11, BIM, Bcl2-L-11, Bcl2-interacting mediator of cell death, BimEL, BimL, BimS
Gene ID 10018
NCBI Accession NP_001191035
UniProt O43521
Pathways PI3K-Akt Signaling, Neurotrophin Signaling Pathway, Tube Formation, Positive Regulation of Endopeptidase Activity

Application Details

Product Details anti-BIM Antibody Target Details BIM Handling Images back to top
Application Notes Western blot: 1: 1000. Immunohistochemistry on frozen sections: 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-BIM Antibody Target Details BIM Application Details Images back to top
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS, 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.