You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-Zebrafish (Danio rerio) MTOR antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended MTOR Antibody (supplied by: Log in to see )

Antigen
Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antibodies
  • 2610315D21Rik
  • AI327068
  • flat
  • FRAP
  • frap1
  • Frap1
  • FRAP1
  • FRAP2
  • RAFT1
  • RAPT1
  • tor
  • wu:fc22h08
Epitope
AA 2440-2457
66
24
24
23
22
21
13
13
13
10
7
6
3
3
3
3
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
340
164
150
8
2
1
1
1
1
Host
Rabbit
292
47
2
Clonality
Polyclonal
Conjugate
This MTOR antibody is un-conjugated
8
7
7
4
4
4
4
4
4
4
4
4
4
3
3
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
221
112
92
62
51
44
32
20
8
7
6
3
2
2
2
2
2
1
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Catalog No. ABIN303334
$ 500.50
Plus shipping costs $45.00

Similar anti-MTOR Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Dog (Canine) Zebrafish (Danio rerio)
Western Blotting (WB) 225 Antibodies 85 Antibodies 79 Antibodies 2 Antibodies 2 Antibodies
Proximity Ligation Assay (PLA) 3 Antibodies 1 Antibodies
Mass Cytometry (CyTOF) 2 Antibodies
Intracellular Staining (ICS) 3 Antibodies 3 Antibodies
Intracellular Flow Cytometry (ICFC) 2 Antibodies
Immunoprecipitation (IP) 37 Antibodies 12 Antibodies 9 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 65 Antibodies

General

Antigen Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) Antibodies
Epitope AA 2440-2457
(66), (24), (24), (23), (22), (21), (13), (13), (13), (10), (7), (6), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Dog (Canine), Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
(340), (164), (150), (8), (2), (1), (1), (1), (1)
Host Rabbit
(292), (47), (2)
Clonality
Polyclonal
Conjugate This MTOR antibody is un-conjugated
(8), (7), (7), (4), (4), (4), (4), (4), (4), (4), (4), (4), (4), (3), (3), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(221), (112), (92), (62), (51), (44), (32), (20), (8), (7), (6), (3), (2), (2), (2), (2), (2), (1)
Supplier Log in to see

Product Details anti-MTOR Antibody

Target Details MTOR Application Details Handling Images
Specificity This antibody recognises MTOR.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Canine (Dog) and Zebrafish.
Species reactivity (tested):Human.
Purification Immunoaffinity Chromatography
Immunogen Synthetic Peptide corresponding to Amino acids 2440-2457 of human mTOR.

Target Details MTOR

Product Details anti-MTOR Antibody Application Details Handling Images back to top
Antigen
Alternative Name mTOR / FRAP1 (FRAP1 Antibody Abstract)
Background The mammalian Target of Rapamycin (TOR, also known as mTOR) is an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors. It was initially discovered as a kinase whose ability to stimulate T cell proliferation in response to IL-2 could be inhibited by the immunosuppressive drug rapamycin. Rapamycin inhibits TOR in other cell types resulting in reduced cell growth and reduced rates of cell cycle and cell proliferation. TOR is normally associated with the regulatory proteins RAPTOR and GbL. Its downstream targets are thought to be the ribosomal protein S6 kinases and the eukaryotic initiation factor 4E binding proteins (4EBPs). Regulation of these protein families allows TOR to control protein biosynthesis.Synonyms: FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, FRAP, FRAP2, Mammalian target of rapamycin, RAPT1, Rapamycin target protein, Serine/threonine-protein kinase mTOR, TOR
Gene ID 2475
NCBI Accession NP_004949
UniProt P42345
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway

Application Details

Product Details anti-MTOR Antibody Target Details MTOR Handling Images back to top
Application Notes Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Immunofluorescence. Western Blot (1/250-1/2000). ELISA (1/4000-1/20000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-MTOR Antibody Target Details MTOR Application Details Images back to top
Concentration 0,6 mg/mL
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Images

Product Details anti-MTOR Antibody Target Details MTOR Application Details Handling back to top
Supplier Images
 image for anti-MTOR antibody (Mechanistic Target of Rapamycin (serine/threonine Kinase)) (AA 2440-2457) (ABIN303334) anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) (AA 2440-2457) antibody
 image for anti-MTOR antibody (Mechanistic Target of Rapamycin (serine/threonine Kinase)) (AA 2440-2457) (ABIN303334) anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (FRAP1) (AA 2440-2457) antibody (Image 2)