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anti-Mouse (Murine) PFKFB2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PFKFB2 Antibody (supplied by: Log in to see )

Antigen
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Antibodies
  • 4930568D07Rik
  • PFK-2/FBPase-2
  • pfkfb2
  • RH2K
  • zgc:56282
Reactivity
Human, Mouse (Murine), Rat (Rattus)
80
39
25
6
4
2
1
Host
Rabbit
76
7
3
Clonality
Polyclonal
Conjugate
This PFKFB2 antibody is un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
64
39
29
11
9
3
2
2
1
1
Supplier
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Catalog No. ABIN272060
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
0.0008913903 ABIN708253 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
0.0008913903 ABIN708260 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
0.0008913903 ABIN708251 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
0.0008913903 ABIN408068 IHC (p) IHC WB Rabbit IgG Pro479 Log in to see Polyclonal

Similar anti-PFKFB2 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 60 Antibodies 29 Antibodies 15 Antibodies
Immunoprecipitation (IP) 3 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 11 Antibodies 5 Antibodies 5 Antibodies
Immunohistochemistry (IHC) 30 Antibodies 7 Antibodies 7 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies 11 Antibodies
Immunofluorescence (IF) 2 Antibodies
Immunocytochemistry (ICC) 2 Antibodies
Immunochromatography (IC) 1 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies
ELISA 39 Antibodies

General

Antigen 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(80), (39), (25), (6), (4), (2), (1)
Host Rabbit
(76), (7), (3)
Clonality
Polyclonal
Conjugate This PFKFB2 antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(64), (39), (29), (11), (9), (3), (2), (2), (1), (1)
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Product Details anti-PFKFB2 Antibody

Target Details PFKFB2 Application Details Handling Images
Specificity This antibody detects endogenous levels of PFKFB2 protein. (region surrounding Pro479)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Purity > 95 % pure by SDS-PAGE

Target Details PFKFB2

Product Details anti-PFKFB2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PFKFB2 (PFKFB2 Antibody Abstract)
Background Phosphofructokinases (PFK) are regulatory glycolytic enzymes that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. Human PFK-1 is tetrameric and isoenzymes include, PFK-1 muscle (PFKM, PFK-A), PFK-1 liver (PFKL, PFK-B) and PFK-1 platelet (PFKP, PFK-C, PFKF). PFK-1 is inhibited by ATP and citrate (from the tricarboxylic acid cycle). PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose 2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose 2,6-bisphosphate and contains fructose 2,6-biphosphatase activity that catalyzes the degradation of fructose 2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4).Synonyms: 6-biphosphatase 2, 6-phosphofructo-2-kinase/fructose-2, PFK-2/FBPase-2, PFK/FBPase 2, PFKFB cardiac
Molecular Weight approx. 58 kDa
Gene ID 5208
NCBI Accession NP_001018063
UniProt O60825
Research Area Cancer, Metabolism
Pathways PI3K-Akt Signaling

Application Details

Product Details anti-PFKFB2 Antibody Target Details PFKFB2 Handling Images back to top
Application Notes ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PFKFB2 Antibody Target Details PFKFB2 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

Images

Product Details anti-PFKFB2 Antibody Target Details PFKFB2 Application Details Handling back to top
Supplier Images
 image for anti-PFKFB2 antibody (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2) (ABIN272060) anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) antibody