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anti-Rat (Rattus) PFKFB2 antibody for Immunohistochemistry (Paraffin-embedded Sections)

Recommended PFKFB2 Antibody (supplied by: Log in to see )

Antigen
6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Antibodies
  • pfkfb2
  • zgc:56282
  • PFK-2/FBPase-2
  • 4930568D07Rik
  • RH2K
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2a
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
  • pfkfb2a
  • PFKFB2
  • pfkfb2
  • Pfkfb2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
87
44
29
7
5
2
1
Host
Rabbit
82
8
3
Clonality
Polyclonal
Conjugate
This PFKFB2 antibody is un-conjugated
3
3
3
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
69
40
33
13
11
4
3
3
1
1
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Catalog No. ABIN272060
$ 390.50
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN408068 IHC (p) IHC WB Rabbit IgG Log in to see Polyclonal
1 ABIN708260 IHC (p) WB HRP Rabbit IgG Log in to see Polyclonal
1 ABIN708253 IHC (p) WB Biotin Rabbit IgG Log in to see Polyclonal
1 ABIN4344997 IHC IHC (p) WB Alexa Fluor 488 Rabbit Log in to see Polyclonal
1 ABIN708251 IF (p) IHC (p) WB Rabbit IgG Log in to see Polyclonal
1 ABIN4344996 IHC IHC (p) WB Alexa Fluor 647 Rabbit Log in to see Polyclonal

Similar anti-PFKFB2 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus)
Western Blotting (WB) 64 Antibodies 33 Antibodies 18 Antibodies
Immunoprecipitation (IP) 4 Antibodies 1 Antibodies
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) 14 Antibodies 7 Antibodies 7 Antibodies
Immunohistochemistry (IHC) 33 Antibodies 9 Antibodies 9 Antibodies
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) 11 Antibodies 11 Antibodies 11 Antibodies
Immunofluorescence (IF) 3 Antibodies
Immunocytochemistry (ICC) 3 Antibodies
Immunochromatography (IC) 1 Antibodies
Enzyme Immunoassay (EIA) 1 Antibodies

General

Antigen 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) Antibodies
Reactivity Human, Mouse (Murine), Rat (Rattus)
(87), (44), (29), (7), (5), (2), (1)
Host Rabbit
(82), (8), (3)
Clonality
Polyclonal
Conjugate This PFKFB2 antibody is un-conjugated
(3), (3), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Application Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(69), (40), (33), (13), (11), (4), (3), (3), (1), (1)
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Product Details anti-PFKFB2 Antibody

Target Details PFKFB2 Application Details Handling Images
Specificity This antibody detects endogenous levels of PFKFB2 protein. (region surrounding Pro479)
Cross-Reactivity (Details) Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.
Purification The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
Purity > 95 % pure by SDS-PAGE

Target Details PFKFB2

Product Details anti-PFKFB2 Antibody Application Details Handling Images back to top
Antigen
Alternative Name PFKFB2 (PFKFB2 Antibody Abstract)
Background Phosphofructokinases (PFK) are regulatory glycolytic enzymes that convert fructose 6-phosphate and ATP into fructose 1,6-bisphosphate (through PFK-1), fructose 2,6-bisphosphate (through PFK-2) and ADP. Human PFK-1 is tetrameric and isoenzymes include, PFK-1 muscle (PFKM, PFK-A), PFK-1 liver (PFKL, PFK-B) and PFK-1 platelet (PFKP, PFK-C, PFKF). PFK-1 is inhibited by ATP and citrate (from the tricarboxylic acid cycle). PFK-1 undergoes activation in the presence of elevated AMP. The most potent activator is fructose 2,6-bisphosphate, which is produced by PFK-2 from the same substrate, fructose 6-phosphate. PFK-2 is bifunctional and a key regulator for PFK-1. PFK-2 catalyzes the synthesis of fructose 2,6-bisphosphate and contains fructose 2,6-biphosphatase activity that catalyzes the degradation of fructose 2,6-bisphosphate. PFK-2 is dimeric and isoenzymes include PFK-2 liver (PFKFB1, PFRX), PFK-2 cardiac (PFKFB2), PFK-2 placental (PFKFB3, inducible PFK-2) and PFK-2 testis (PFKFB4).Synonyms: 6-biphosphatase 2, 6-phosphofructo-2-kinase/fructose-2, PFK-2/FBPase-2, PFK/FBPase 2, PFKFB cardiac
Molecular Weight approx. 58 kDa
Gene ID 5208
NCBI Accession NP_001018063
UniProt O60825
Research Area Cancer, Metabolism
Pathways PI3K-Akt Signaling

Application Details

Product Details anti-PFKFB2 Antibody Target Details PFKFB2 Handling Images back to top
Application Notes ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-PFKFB2 Antibody Target Details PFKFB2 Application Details Images back to top
Concentration 1,0 mg/mL
Buffer Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice DO NOT FREEZE!
Storage 4 °C
Storage Comment Store the antibody undiluted at 2-8 °C.

Images

Product Details anti-PFKFB2 Antibody Target Details PFKFB2 Application Details Handling back to top
Supplier Images
 image for anti-PFKFB2 antibody (6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2) (ABIN272060) anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 2 (PFKFB2) antibody