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anti-Rat (Rattus) PIP5K1C antibody for Immunofluorescence

Recommended PIP5K1C Antibody (supplied by: Log in to see )

Antigen
Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) Antibodies
  • AI115456
  • AI835305
  • LCCS3
  • MGC130766
  • PIP5K-GAMMA
  • pip5k1a
  • PIP5K1C
  • PIP5Kgamma
  • Pip5kIgamma
  • PIPKIg_v4
  • si:dkey-29i9.1
  • zgc:110576
Epitope
AA 479-580
10
9
4
3
2
2
2
1
1
1
1
1
Reactivity
Mouse (Murine), Rat (Rattus)
39
5
4
2
Host
Mouse
34
5
Clonality
Monoclonal
Conjugate
This PIP5K1C antibody is un-conjugated
2
2
2
2
2
2
Application
Immunofluorescence (IF), Western Blotting (WB)
36
27
13
4
2
2
1
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Catalog No. ABIN968393
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Top referenced anti-PIP5K1C antibody for Immunofluorescence

Similar anti-PIP5K1C Antibodies

Application / Reactivity Rat (Rattus) Mouse (Murine)
ELISA 2 Antibodies 2 Antibodies
Immunofluorescence (IF) 1 Antibodies 1 Antibodies
Immunohistochemistry (IHC) 1 Antibodies 1 Antibodies
Western Blotting (WB) 4 Antibodies 5 Antibodies

General

Antigen Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) Antibodies
Epitope AA 479-580
(10), (9), (4), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity Mouse (Murine), Rat (Rattus)
(39), (5), (4), (2)
Host Mouse
(34), (5)
Clonality (Clone)
Monoclonal   ( )
Conjugate This PIP5K1C antibody is un-conjugated
(2), (2), (2), (2), (2), (2)
Application Immunofluorescence (IF), Western Blotting (WB)
(36), (27), (13), (4), (2), (2), (1)
Pubmed 3 references available
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Product Details anti-PIP5K1C Antibody

Target Details PIP5K1C Application Details Handling References for anti-PIP5K1C Antibody (ABIN968393) Images
Cross-Reactivity Rat (Rattus)
Characteristics 1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
Purification The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
Immunogen Mouse PIP5Kgamma aa. 479-580
Clone 12-PIP5Kgamma
Isotype IgG1

Target Details PIP5K1C

Product Details anti-PIP5K1C Antibody Application Details Handling References for anti-PIP5K1C Antibody (ABIN968393) Images back to top
Antigen
Alternative Name PIP5K gamma (PIP5K1C Antibody Abstract)
Background Phosphoinositide turnover is a well established mechanism of intracellular signal transduction. Sequential phosphorylation of phosphatidylinositol (PtdIns) results in PtdIns(4)P (PIP) and PtdIns(4,5)P2 (PIP2). Phospholipase C (PLC) hydrolyzes PIP2 to inositol (1,4,5)P3 (IP3) which stimulates release of intracellular Ca2+. PIP2 is generated by phosphorylation of PtdIns 5-kinases (PI5-K). These enzymes are divided into two types (I and II) based on their size and sensitivity to certain compounds. Three mammalian PI5-Ks, PI5-Kalpha, beta, and gamma of type I have been identified and a type II PIP5kalpha. Although the PI4-Ks are abundantly distributed throughout the cell, activity is found primarily in association with membranous structures. Members of this family contain a lipid kinase unique domain and a C-terminal catalytic domain.
Molecular Weight 87-90 kDa
Pathways PI3K-Akt Signaling

Application Details

Product Details anti-PIP5K1C Antibody Target Details PIP5K1C Handling References for anti-PIP5K1C Antibody (ABIN968393) Images back to top
Comment

Related Products: ABIN968545, ABIN967389

Restrictions For Research Use only

Handling

Product Details anti-PIP5K1C Antibody Target Details PIP5K1C Application Details References for anti-PIP5K1C Antibody (ABIN968393) Images back to top
Format Liquid
Concentration 250 μg/mL
Buffer Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store undiluted at -20°C.

References for anti-PIP5K1C Antibody (ABIN968393)

Product Details anti-PIP5K1C Antibody Target Details PIP5K1C Application Details Handling Images back to top
Product cited in:

Ishihara, Shibasaki, Kizuki, Wada, Yazaki, Asano, Oka: "Type I phosphatidylinositol-4-phosphate 5-kinases. Cloning of the third isoform and deletion/substitution analysis of members of this novel lipid kinase family." in: The Journal of biological chemistry, Vol. 273, Issue 15, pp. 8741-8, 1998

Nishikawa, Toker, Wong, Marignani, Johannes, Cantley: "Association of protein kinase Cmu with type II phosphatidylinositol 4-kinase and type I phosphatidylinositol-4-phosphate 5-kinase." in: The Journal of biological chemistry, Vol. 273, Issue 36, pp. 23126-33, 1998

Tolias, Rameh, Ishihara, Shibasaki, Chen, Prestwich, Cantley, Carpenter: "Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphate." in: The Journal of biological chemistry, Vol. 273, Issue 29, pp. 18040-6, 1998

Images

Product Details anti-PIP5K1C Antibody Target Details PIP5K1C Application Details Handling References for anti-PIP5K1C Antibody (ABIN968393) back to top
Supplier Images
Western Blotting (WB) image for anti-PIP5K1C antibody (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma) (AA 479-580) (ABIN968393) Western blot analysis of PIP5Kgamma on a rat cerebrum lysate. Lane 1: 1:250, lane 2: ...
Immunofluorescence (IF) image for anti-PIP5K1C antibody (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma) (AA 479-580) (ABIN968393) Immunofluorescence staining of PC12 cells (Rat neuroblastoma, ATCC CRL-1721).
 image for anti-PIP5K1C antibody (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma) (AA 479-580) (ABIN968393) anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (AA 479-580) antibody (Image 3)
Western Blotting (WB) image for anti-PIP5K1C antibody (Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma) (AA 479-580) (ABIN968393) anti-Phosphatidylinositol-4-Phosphate 5-Kinase, Type I, gamma (PIP5K1C) (AA 479-580) antibody (Image 4)