anti-Mouse (Murine) RPS6KB1 antibody for Enzyme Immunoassay

Recommended RPS6KB1 Antibody (supplied by: Log in to see )

Antigen
Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) Antibodies
  • PS6K
  • S6K
  • S6K-beta-1
  • S6K1
  • STK14A
  • p70 S6KA
  • p70(S6K)-alpha
  • p70-S6K
  • p70-alpha
  • XPKAbeta
  • pkacb
  • 10539
  • 7084
  • CG10539
  • DS6K
  • Dmel\\CG10539
  • Dp70S6k
  • Dp70[s6k]
  • Dp70s6k
  • S6k
  • dS6K
  • dS6k
  • dp70[S6k]
  • dp70s6k
  • dps6k
  • ds6k
  • fs(3)07084
  • l(3)07084
  • p70 S6K
  • p70/S6K
  • p70S6K
  • p70[S6 kinase]
  • p70[S6K]
  • p70[S6k]
  • p70[S6kinase]
  • p70s6K
  • s6k
  • s6k11
  • 2610318I15Rik
  • 4732464A07Rik
  • 70kDa
  • AA959758
  • AI256796
  • AI314060
  • p70/85s6k
  • p70s6k
  • p70s6k-A
  • ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • protein kinase, cAMP-dependent, catalytic, beta
  • RPS6-p70-protein kinase
  • ribosomal protein S6 kinase, polypeptide 1
  • p70 S6 kinase
  • RPS6KB1
  • prkacb
  • S6k
  • Rps6kb1
  • p70s6k-A
Epitope
C-Term
100
36
30
28
24
23
20
20
20
19
18
18
17
16
15
15
15
14
14
11
11
8
7
6
6
6
5
5
5
5
5
5
5
4
4
3
3
3
3
3
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
689
445
422
72
53
41
34
33
21
13
13
8
5
5
3
3
1
Host
Rabbit
616
53
23
2
Clonality
Polyclonal
Conjugate
This RPS6KB1 antibody is un-conjugated
24
22
21
14
13
13
9
9
9
9
9
8
8
8
8
8
8
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
527
265
253
143
131
104
64
36
22
20
17
11
5
1
1
1
1
Supplier
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Catalog No. ABIN5551331
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5552808 EIA IHC (p) WB Goat C-Term Log in to see Polyclonal
1 ABIN401355 EIA IP WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN303144 EIA IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal

Similar anti-RPS6KB1 Antibodies

Application / Reactivity Human Mouse (Murine) Rat (Rattus) Cow (Bovine)
Immunofluorescence (fixed cells) (IF/ICC) 17 Antibodies 15 Antibodies 15 Antibodies 9 Antibodies
Simple Western (SimWes) 1 Antibodies 1 Antibodies 1 Antibodies
Western Blotting (WB) 313 Antibodies 292 Antibodies 69 Antibodies 522 Antibodies
Radioimmunoassay (RIA) 1 Antibodies 1 Antibodies 1 Antibodies
Proximity Ligation Assay (PLA) 1 Antibodies
Immunoprecipitation (IP) 64 Antibodies 43 Antibodies

General

Antigen Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) Antibodies
Epitope C-Term
(100), (36), (30), (28), (24), (23), (20), (20), (20), (19), (18), (18), (17), (16), (15), (15), (15), (14), (14), (11), (11), (8), (7), (6), (6), (6), (5), (5), (5), (5), (5), (5), (5), (4), (4), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(689), (445), (422), (72), (53), (41), (34), (33), (21), (13), (13), (8), (5), (5), (3), (3), (1)
Host Rabbit
(616), (53), (23), (2)
Clonality
Polyclonal
Conjugate This RPS6KB1 antibody is un-conjugated
(24), (22), (21), (14), (13), (13), (9), (9), (9), (9), (9), (8), (8), (8), (8), (8), (8), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunoprecipitation (IP), Western Blotting (WB)
(527), (265), (253), (143), (131), (104), (64), (36), (22), (20), (17), (11), (5), (1), (1), (1), (1)
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Product Details anti-RPS6KB1 Antibody

Target Details RPS6KB1 Application Details Handling Images
Specificity This antibody detects a ~70 kDa protein, corresponding to the molecular mass of p70 S6K on SDS-PAGE immunoblots.
Cross-Reactivity (Details) Species reactivity (tested):Human, Mouse, Rat, Bovine
Purification Affinity Chromatography
Immunogen Human p70 S6K C-terminal peptide - KLH conjugates
Isotype IgG

Target Details RPS6KB1

Product Details anti-RPS6KB1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name RPS6KB1 / STK14A (RPS6KB1 Antibody Abstract)
Background Ribosomal S6 (S6K) belongs to the AGC family of Serine/Threonine protein kinases. There are two forms of S6K, alpha and beta, which have cytoplasmic and nuclear variants derived from alternative splicing (1). The activity of S6K is regulated by phosphorylation/dephosphorylation events in cellular responses to various extracellular stimuli. Its activity has also been shown to be dependent on nutrient availability (3-6). The mechanism of activation of S6K is a multi-step process which is achieved by phosphorylating the 40S ribosomal protein S6, which then upregulates the translation of mRNA transcripts containing an oligopryimidine tract at the 5' transcriptional start site (3-6). Recently, a highly homologous ribosomal S6 kinase, termed S6K2, was identified. It has 70 % amino acid identity in the overall sequence with S6K1, and highly conserved potential phosphorylation sites of S6K1. However, the N- and Cterminal domains of S6K2 are quite different (2). As a result, S6K is a key player in the regulation of cell size, growth and glucose homeostasis.Synonyms: 70 kDa ribosomal protein S6 kinase 1, Ribosomal protein S6 kinase I, Ribosomal protein S6 kinase beta-1, S6K-beta-1, S6K1, Serine/threonine-protein kinase 14A, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, p70-S6K 1
Gene ID 6198
NCBI Accession NP_003152
UniProt P23443
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma

Application Details

Product Details anti-RPS6KB1 Antibody Target Details RPS6KB1 Handling Images back to top
Application Notes Western blot (1): 0.25 μg/mL. Immunoprecipitation (1). ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-RPS6KB1 Antibody Target Details RPS6KB1 Application Details Images back to top
Format Liquid
Concentration 0.25 mg/mL
Buffer TBS, 0.09 % Sodium Azide, 50 % Glycerol
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.