anti-Mouse (Murine) RPS6KB1 antibody for Enzyme Immunoassay

Recommended RPS6KB1 Antibody (supplied by: Log in to see )

Antigen
Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) Antibodies
  • PS6K
  • S6K
  • S6K-beta-1
  • S6K1
  • STK14A
  • p70 S6KA
  • p70(S6K)-alpha
  • p70-S6K
  • p70-alpha
  • XPKAbeta
  • pkacb
  • 10539
  • 7084
  • CG10539
  • DS6K
  • Dmel\\CG10539
  • Dp70S6k
  • Dp70[s6k]
  • Dp70s6k
  • S6k
  • dS6K
  • dS6k
  • dp70[S6k]
  • dp70s6k
  • dps6k
  • ds6k
  • fs(3)07084
  • l(3)07084
  • p70 S6K
  • p70/S6K
  • p70S6K
  • p70[S6 kinase]
  • p70[S6K]
  • p70[S6k]
  • p70[S6kinase]
  • p70s6K
  • s6k
  • s6k11
  • 2610318I15Rik
  • 4732464A07Rik
  • 70kDa
  • AA959758
  • AI256796
  • AI314060
  • p70/85s6k
  • p70s6k
  • p70s6k-A
  • ribosomal protein S6 kinase, 70kDa, polypeptide 1
  • protein kinase, cAMP-dependent, catalytic, beta
  • RPS6-p70-protein kinase
  • ribosomal protein S6 kinase, polypeptide 1
  • p70 S6 kinase
  • RPS6KB1
  • prkacb
  • S6k
  • Rps6kb1
  • p70s6k-A
Epitope
C-Term
107
40
38
30
29
21
21
20
20
18
18
17
15
15
15
14
14
14
12
11
10
9
8
6
6
6
6
5
5
5
5
5
4
3
3
3
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
719
455
432
72
54
40
34
33
21
13
13
8
5
5
3
3
1
Host
Goat
638
62
22
2
Clonality
Polyclonal
Conjugate
This RPS6KB1 antibody is un-conjugated
24
22
21
15
13
13
10
10
10
10
10
8
8
8
8
8
8
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
548
284
257
152
132
104
67
42
32
20
17
11
6
4
2
1
1
1
Supplier
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Catalog No. ABIN5552808
$ 375.38
Plus shipping costs $45.00
Relevance Score ABIN Application Conjugate Host Isotype Epitope Supplier Clonality References Details
1 ABIN5551331 EIA IP WB Rabbit IgG C-Term Log in to see Polyclonal
1 ABIN303144 EIA IHC (p) IP WB Rabbit C-Term Log in to see Polyclonal

General

Antigen Ribosomal Protein S6 Kinase, 70kDa, Polypeptide 1 (RPS6KB1) Antibodies
Epitope C-Term
(107), (40), (38), (30), (29), (21), (21), (20), (20), (18), (18), (17), (15), (15), (15), (14), (14), (14), (12), (11), (10), (9), (8), (6), (6), (6), (6), (5), (5), (5), (5), (5), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Rat (Rattus)
(719), (455), (432), (72), (54), (40), (34), (33), (21), (13), (13), (8), (5), (5), (3), (3), (1)
Host Goat
(638), (62), (22), (2)
Clonality
Polyclonal
Conjugate This RPS6KB1 antibody is un-conjugated
(24), (22), (21), (15), (13), (13), (10), (10), (10), (10), (10), (8), (8), (8), (8), (8), (8), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(548), (284), (257), (152), (132), (104), (67), (42), (32), (20), (17), (11), (6), (4), (2), (1), (1), (1)
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Product Details anti-RPS6KB1 Antibody

Target Details RPS6KB1 Application Details Handling Images
Sequence C-MISKRPEHLR MNL
Specificity This antibody detects RPS6KB1 at C-term.
Cross-Reactivity (Details) Species reactivity (expected):Mouse, Rat, Canine (Dog), Bovine.
Species reactivity (tested):Human.
Purification Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
Immunogen Peptide from the C Terminus of the protein sequence according to NP_003152.1 Genename: RPS6KB1

Target Details RPS6KB1

Product Details anti-RPS6KB1 Antibody Application Details Handling Images back to top
Antigen
Alternative Name RPS6KB1 / STK14A (RPS6KB1 Antibody Abstract)
Background The protein p70 S6 kinase is critical for cell cycle progression and cell survival. In response to mitogen stimulation, p70 S6 kinase activation up-regulates ribosomal biosynthesis and enhances the translational capacity. p70S6K phosphorylates the S6 protein of the 40S subunit of the ribosome. This kinase was first characterized as an insulin/mitogen-activated protein kinase, whose major known substrate is the 40 S ribosomal subunit protein S6. The p70 S6 kinase is activated by diverse stimuli through a multi-site phosphorylation such as Thr-252 and Ser-434. In Alzheimer's Disease (AD), p70 S6 kinase activation is associated with PHF-tau (hyperphosphorylated tau) accumulation. In non-neuronal cells, p70 S6 kinase have been shown to regulate actin polymerization.Synonyms: 70 kDa ribosomal protein S6 kinase 1, Ribosomal protein S6 kinase I, Ribosomal protein S6 kinase beta-1, S6K-beta-1, S6K1, Serine/threonine-protein kinase 14A, p70 S6 kinase alpha, p70 S6K-alpha, p70 S6KA, p70-S6K 1
Molecular Weight 60kDa according to NP_003152.1
Gene ID 6198
NCBI Accession NP_003152
UniProt P23443
Pathways PI3K-Akt Signaling, RTK Signaling, AMPK Signaling, Regulation of Cell Size, Skeletal Muscle Fiber Development, Feeding Behaviour, G-protein mediated Events, Smooth Muscle Cell Migration, Interaction of EGFR with phospholipase C-gamma

Application Details

Product Details anti-RPS6KB1 Antibody Target Details RPS6KB1 Handling Images back to top
Application Notes Peptide ELISA: Detection Limit: 1/128000. Western blot: 0.2-1 μg/mL. Detects a band of Approx 65-70 kDa in Human Skeletal Muscle and Placenta lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions For Research Use only

Handling

Product Details anti-RPS6KB1 Antibody Target Details RPS6KB1 Application Details Images back to top
Concentration 0.5 mg/mL
Buffer Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.