Browse our CYR61 Proteins (CYR61)

Full name:
Cysteine-Rich, Angiogenic Inducer, 61 Proteins (CYR61)
On www.antibodies-online.com are 23 Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) Proteins from 9 different suppliers available. Additionally we are shipping CYR61 Antibodies (190) and CYR61 Kits (24) and many more products for this protein. A total of 243 CYR61 products are currently listed.
Synonyms:
AI325051, CCN1, CYR61, cyr61-l2, GIG1, IGFBP10, MGC69281, MGC69539, smt3a, smt3h1, sumo-3, Xcyr61, zgc:158158
list all proteins Gene Name GeneID UniProt
CYR61 16007 P18406
CYR61 3491 O00622
CYR61 83476 Q9ES72

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CYR61 Proteins (CYR61) by Origin

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Top referenced CYR61 Proteins

  1. Human CYR61 Protein expressed in Wheat germ - ABIN1351026 : Jeansonne, Pacifici, Lassak, Reiss, Russo, Zabaleta, Peruzzi: Differential Effects of MicroRNAs on Glioblastoma Growth and Migration. in Genes 2014 (PubMed)
    Show all 16 references for 1351026

More Proteins for CYR61 Interaction Partners

Mouse (Murine) Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) interaction partners

  1. Our results not only reveal a novel mechanism illustrating the role of Cyr61 in epidermis pathogenesis but also suggest that therapies targeting Cyr61 may represent a novel strategy in the treatment of psoriasis vulgaris.

  2. The LPA1 (show LPAR1 Proteins)-CCN1 (show CCNA2 Proteins) axis may be the central control for SMC (show DYM Proteins) migration.

  3. these data suggest that the WNT (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway enhances pancreatic cancer development and malignancy in part via up-regulation of CYR61.

  4. Lysophosphatidic acid induced time-dependent phosphorylation of serum response factor and CRE-binding protein in in smooth muscle cells, inducing transcription of CCN1 (show CCNA2 Proteins).

  5. Data show that Cysteine-rich 61 (CYR61) acts as a tumor-promoting gene in pancreatic neuroendocrine tumors.

  6. CCN1 (show CCNA2 Proteins) is an important regulator of chondrocyte maturation during cartilage development and homeostasis.

  7. CCN1 (show CCNA2 Proteins) exacerbates tracheal obliterative bronchiolitis by enhancing fibroproliferation via an alphavbeta3-integrin-independent pathway.

  8. Data show that RNA silencing of CCN family member 1 protein (CCN1 (show CCNA2 Proteins)) inhibits retinal neovascularization (RNV) by inhibiting phosphoinositide 3-kinase (PI3K)/AKT protein signaling in mouse pup model of oxyge (show AKT1 Proteins)n-induced retinopathy (OIR).

  9. These findings reveal a critical role for CCN1 (show CCNA2 Proteins) in restoring mucosal homeostasis after intestinal injury

  10. CCN1 (show CCNA2 Proteins) is an injury response protein that functions not only to restrict fibrosis in the liver, but also to suppress hepatocarcinogenesis by inhibiting EGFR (show EGFR Proteins)-dependent hepatocyte compensatory proliferation

Human Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) interaction partners

  1. CYR61 is a TGF-beta (show TGFB1 Proteins)-induced stromal-derived factor that regulates gemcitabine sensitivity in pancreatic ductal adenocarcinoma.

  2. These studies support previously unrecognized, cooperative interaction between the CCN1 (show CCNA2 Proteins) matricellular protein and canonical TGF-beta1 (show TGFB1 Proteins)/SMAD3 (show SMAD3 Proteins) signaling that promotes lung fibrosis.

  3. Our data indicate a potential functional impact of Cyr61 in development and the progression of cervical cancer

  4. results highlight both CYR61 and TAZ (show TAZ Proteins) genes as potential predictive biomarkers for stratification of the risk for development of adenocarcinoma and suggest a potential mechanistic route for Barrett's esophagus neoplastic progression

  5. Reduced levels of CCN1 (show CCNA2 Proteins) and CCN3 (show NOV Proteins), as found in early-onset preeclampsia, could contribute to a shift from invasive to proliferative extravillous trophoblasts and may explain their shallow invasion properties in this disease.

  6. Promoter activity was determined as well as CYR61 mRNA and protein expression.

  7. Our results not only reveal a novel mechanism illustrating the role of Cyr61 in epidermis pathogenesis but also suggest that therapies targeting Cyr61 may represent a novel strategy in the treatment of psoriasis vulgaris.

  8. Results provide evidence that CCN1 (show CCNA2 Proteins) can stimulate the proliferation and differentiation of osteoblasts in vitro and contribute to bone remodeling in vivo in myeloma bone disease.

  9. these data suggest that the WNT (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling pathway enhances pancreatic cancer development and malignancy in part via up-regulation of CYR61.

  10. CCN1 (show CCNA2 Proteins) RNAi reduced the mRNA and protein expression levels of CCN1 (show CCNA2 Proteins), Akt (show AKT1 Proteins) and VEGF (show VEGFA Proteins) in the HUVECs (P<0.05). Furthermore, LY294002 reduced the mRNA and protein expression levels of CCN1 (show CCNA2 Proteins) in the hypoxic cells (P<0.05). Therefore, CCN1 (show CCNA2 Proteins) RNAi may offer a novel therapeutic strategy, which may aid in the treatment of pathological angiogenesis via inhibition of the PI3K (show PIK3CA Proteins)/AktVEGF pathway

Cow (Bovine) Cysteine-Rich, Angiogenic Inducer, 61 (CYR61) interaction partners

  1. The increased expression of CYR61 in the Day 4 corpus lutum (CL) and its transient increase by prostaglandin F2alpha in Day 6, Day 10, and Day 16 CL indicate that CYR61 may play a role in regulating angiogenesis over the life span of the CL.

  2. Together, these results indicate that Cyr61 is an important determinant of the genetic reprogramming that occurs in mechanically challenged cells.

  3. Mechanical regulation of the Cyr61 gene in smooth muscle cells

CYR61 Protein Profile

Protein Summary

The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation.

Alternative names and synonyms associated with CYR61

  • cysteine-rich, angiogenic inducer, 61 (cyr61)
  • cysteine-rich, angiogenic inducer, 61 (CYR61)
  • small ubiquitin-like modifier 3 (sumo3)
  • cysteine-rich, angiogenic inducer, 61 (LOC100230216)
  • cysteine rich protein 61 (Cyr61)
  • cysteine-rich, angiogenic inducer, 61 (Cyr61)
  • AI325051 protein
  • CCN1 protein
  • CYR61 protein
  • cyr61-l2 protein
  • GIG1 protein
  • IGFBP10 protein
  • MGC69281 protein
  • MGC69539 protein
  • smt3a protein
  • smt3h1 protein
  • sumo-3 protein
  • Xcyr61 protein
  • zgc:158158 protein

Protein level used designations for CYR61

cysteine-rich, angiogenic inducer, 61 , SMT3 suppressor of mif two 3 homolog 3 , small ubiquitin-related modifier 3 , protein CYR61-like , 3CH61 , CCN family member 1 , IBP-10 , IGF-binding protein 10 , IGFBP-10 , cysteine-rich angiogenic inducer 61 , insulin-like growth factor binding protein 10 , insulin-like growth factor-binding protein 10 , intermediate early , protein CYR61 , cysteine-rich heparin-binding protein 61 , cysteine-rich, anigogenic inducer, 61 , cysteine rich protein 61 , secreted cysteine-rich protein cyr61

GENE ID SPECIES
448140 Xenopus (Silurana) tropicalis
553273 Danio rerio
714970 Macaca mulatta
100125978 Xenopus (Silurana) tropicalis
100230216 Taeniopygia guttata
100413443 Callithrix jacchus
100445022 Pongo abelii
100471762 Ailuropoda melanoleuca
16007 Mus musculus
3491 Homo sapiens
83476 Rattus norvegicus
429089 Gallus gallus
379598 Xenopus laevis
479967 Canis lupus familiaris
508941 Bos taurus
456988 Pan troglodytes
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