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CYR61 Products

(Cysteine-Rich, Angiogenic Inducer, 61 (CYR61))
The secreted protein encoded by this gene is growth factor-inducible and promotes the adhesion of endothelial cells. The encoded protein interacts with several integrins and with heparan sulfate proteoglycan. This protein also plays a role in cell proliferation, differentiation, angiogenesis, apoptosis, and extracellular matrix formation. [provided by RefSeq, Sep 2011].

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Featured CYR61 Categories

CYR61 Antibodies

High quality antibodies with extensive validation data.

CYR61 ELISA Kits

Reliable ELISA kits for a wide range of species.

CYR61 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CYR61 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
  • (7)
Cat. No. ABIN7436243
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (7)
Cat. No. ABIN7439291
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN674499
Quantity 100 μL
Datasheet Datasheet

Recommended CYR61 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
Cat. No. ABIN6955198
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6976203
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962250
Quantity 96 tests
Datasheet Datasheet

Recommended CYR61 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (16)
  • (1)
Cat. No. ABIN1351026
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122563
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1351029
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our CYR61 products

Otani, Ishida, Kurozumi, Oka, Shimizu, Tomita, Hattori, Uneda, Matsumoto, Michiue, Tomida, Matsubara, Ichikawa, Date: "PIK3R1Met326Ile germline mutation correlates with cysteine-rich protein 61 expression and poor prognosis in glioblastoma." in: Scientific reports, Vol. 7, Issue 1, pp. 7391, (2019) (PubMed).

Hellinger, Hüchel, Goetz, Bauerschmitz, Emons, Gründker: "Inhibition of CYR61-S100A4 Axis Limits Breast Cancer Invasion." in: Frontiers in oncology, Vol. 9, pp. 1074, (2019) (PubMed).

Sun, Huang, Xu, Sun, Lv, Wang: "Advanced glycation end products promote VEGF expression and thus choroidal neovascularization via Cyr61-PI3K/AKT signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 14925, (2017) (PubMed).

Chin, Hsu, Zhong, Liang: "Involvement of cysteine-rich protein 61 in the epidermal growth factor-induced migration of human anaplastic thyroid cancer cells." in: Molecular carcinogenesis, Vol. 55, Issue 5, pp. 622-32, (2016) (PubMed).

Li, Adur, Kannan, Davila, Zhao, Nowak, Bagchi, Bagchi, Li: "Progesterone Alleviates Endometriosis via Inhibition of Uterine Cell Proliferation, Inflammation and Angiogenesis in an Immunocompetent Mouse Model." in: PLoS ONE, Vol. 11, Issue 10, pp. e0165347, (2016) (PubMed).

Chin, Hsu, Zhong, Liang: "Combined treatment with troglitazone and lovastatin inhibited epidermal growth factor-induced migration through the downregulation of cysteine-rich protein 61 in human anaplastic thyroid cancer cells." in: PLoS ONE, Vol. 10, Issue 3, pp. e0118674, (2015) (PubMed).

Li, Pishdari, Cui, Hu, Yang, Guo, Jiang, Feng, Billig, Shao: "Regulation of Androgen Receptor Expression Alters AMPK Phosphorylation in the Endometrium: In Vivo and In Vitro Studies in Women with Polycystic Ovary Syndrome." in: International journal of biological sciences, Vol. 11, Issue 12, pp. 1376-89, (2015) (PubMed).

Jeansonne, Pacifici, Lassak, Reiss, Russo, Zabaleta, Peruzzi: "Differential Effects of MicroRNAs on Glioblastoma Growth and Migration." in: Genes, Vol. 4, Issue 1, pp. 46-64, (2014) (PubMed).

Zhou, Zhang, Chen, Su, Jin, Wang, Hu, Ke, Song: "Potential role of Cyr61 induced degeneration of human Müller cells in diabetic retinopathy." in: PLoS ONE, Vol. 9, Issue 10, pp. e109418, (2014) (PubMed).

Catoire, Mensink, Kalkhoven, Schrauwen, Kersten: "Identification of human exercise-induced myokines using secretome analysis." in: Physiological genomics, Vol. 46, Issue 7, pp. 256-67, (2014) (PubMed).

Synonyms and alternative names related to CYR61

cysteine rich angiogenic inducer 61 (CYR61), cysteine-rich, angiogenic inducer, 61 (Cyr61), cysteine rich angiogenic inducer 61 (cyr61), cysteine-rich, angiogenic inducer, 61 like 2 (cyr61l2), cysteine rich protein 61 (Cyr61), cysteine rich angiogenic inducer 61 S homeolog (cyr61.S), cysteine rich angiogenic inducer 61 (Cyr61), AI325051, CCN1, ccn1, CYR61, cyr61-l2, GIG1, gig1, IGFBP10, igfbp10, Igfbp10, MGC69281, MGC69539, Xcyr61, zgc:158158

Protein level used designations for CYR61

  • CCN family member 1
  • IBP-10
  • IGF-binding protein 10
  • IGFBP-10
  • cysteine-rich heparin-binding protein 61
  • cysteine-rich, anigogenic inducer, 61
  • insulin-like growth factor-binding protein 10
  • protein CYR61
  • cysteine rich protein 61
  • cysteine-rich, angiogenic inducer, 61
  • cysteine-rich angiogenic inducer 61
  • protein CYR61-like
  • 3CH61
  • insulin-like growth factor binding protein 10
  • intermediate early
  • secreted cysteine-rich protein cyr61
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