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Expression and clinicopathological significance of human growth and transformation-dependent protein (HGTD-P) in uterine cervical cancer
Data indicate that HGTD-P is a new hypoxia-inducible factor 1 alpha (show HIF1A Proteins)-responsive proapoptotic molecule that activates mitochondrial apoptotic cascades.
Heat shock protein 90 (show HSP90 Proteins) physically interacts with HGTD-P.
human growth and transformation-dependent protein expression is a common occurrence during the progression from a normal gastric mucosa to an intestinal-type carcinoma and may be associated with tumor cell proliferation activity
HGTD-P plays a proapoptotic role in the developing rat brain following hypoxia-ischemia by activating caspase 3 (show CASP3 Proteins) and inducing the translocation of apoptosis-inducing factor (AIF (show AIFM1 Proteins)) to the nucleus.
may be involved in cell proliferation
E2-induced gene 5 protein
, HIF-1 alpha-responsive proapoptotic molecule
, growth and transformation-dependent protein
, protein FAM162A
, E2-induced gene 5 protein homolog