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anti-Mouse (Murine) KPNA6 Antibodies:
anti-Human KPNA6 Antibodies:
anti-Rat (Rattus) KPNA6 Antibodies:
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Human Polyclonal KPNA6 Primary Antibody for IHC (p), IHC - ABIN408712
Ma, Cao: Regulation of Stat3 nuclear import by importin alpha5 and importin alpha7 via two different functional sequence elements. in Cellular signalling 2006
Data shows that Importin 7 (show IPO7 Antibodies) binds many partners from ovary that alpha are involved in RNA processing, chromosome organization, and chromatin modification.
Importin alpha7 is a new member of the small group of maternal effect (show NLRP5 Antibodies) genes.
Overexpression of Kpna6 facilitates Keap1 (show KEAP1 Antibodies) nuclear import and attenuates Nrf2 (show NFE2L2 Antibodies) signaling, whereas knockdown of Kpna6 slows down Keap1 (show KEAP1 Antibodies) nuclear import and enhances the Nrf2 (show NFE2L2 Antibodies)-mediated adaptive response induced by oxidative stress.
a decreased H7N9 influenza A virus polymerase activity when importin-alpha7 was silenced by siRNA, is reported.
BIG3 (show WDR5 Antibodies) may block the KPNAs (KPNA1 (show KPNA1 Antibodies), KPNA5 (show KPNA5 Antibodies), and KPNA6) binding region(s) of PHB2 (show PHB2 Antibodies).
Bel1 fragment with residues 215-223, which bears the NLS (show ALDH1A2 Antibodies), interacts with KPNA1 (show KPNA1 Antibodies), KPNA6, and KPNA7.
Importin alpha1 and alpha7 are positive regulators of human-like polymerase activity and pathogenicity beyond their role in nuclear transport.
Overexpression of KPNA6 facilitates KEAP1 (show KEAP1 Antibodies) nuclear import and attenuates NRF2 (show GABPA Antibodies) signaling, whereas knockdown of KPNA6 slows down KEAP1 (show KEAP1 Antibodies) nuclear import and enhances the NRF2 (show GABPA Antibodies)-mediated adaptive response induced by oxidative stress.
Importin alpha5 and alpha7 bind to Stat3 (show STAT3 Antibodies) upon cytokine stimulation.
Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. The protein encoded by this gene is a member of the importin alpha family.
karyopherin alpha 6 (importin alpha 7)
, importin subunit alpha-7-like
, importin alpha-S2
, importin subunit alpha-7
, karyopherin (importin) alpha 5
, karyopherin subunit alpha-6
, importin alpha 7 subunit
, karyopherin (importin) alpha 6
, imp alpha 5
, importin alpha 5.2 protein
, Importin subunit alpha-7