Browse our PTTG1IP Proteins (PTTG1IP)

Full name:
Pituitary Tumor-Transforming 1 Interacting Protein Proteins (PTTG1IP)
On www.antibodies-online.com are 6 Pituitary Tumor-Transforming 1 Interacting Protein (PTTG1IP) Proteins from 4 different suppliers available. Additionally we are shipping PTTG1IP Antibodies (24) and PTTG1IP Kits (21) and many more products for this protein. A total of 54 PTTG1IP products are currently listed.
Synonyms:
1810010L20Rik, AI314311, AU018448, C21orf1, C21orf3, C79540, PBF
list all proteins Gene Name GeneID UniProt
PTTG1IP 108705 Q8R143
Rat PTTG1IP PTTG1IP 365548 Q6P767
PTTG1IP 754 P53801

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PTTG1IP Proteins (PTTG1IP) by Origin

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More Proteins for PTTG1IP Interaction Partners

Mouse (Murine) Pituitary Tumor-Transforming 1 Interacting Protein (PTTG1IP) interaction partners

  1. protooncogene PBF is a negative regulator of p53 (show TP53 Proteins) function in thyroid tumorigenesis, in which PBF is generally overexpressed and p53 (show TP53 Proteins) mutations are rare compared with other tumor types

Human Pituitary Tumor-Transforming 1 Interacting Protein (PTTG1IP) interaction partners

  1. Findings indicate that PBF and PTTG (show PTTG1 Proteins) have a critical role in promoting thyroid cancer that is predictive of poorer patient outcome.

  2. Unique role for PBF in regulating CTTN (show CTTN Proteins) function to promote endocrine cell invasion and migration.

  3. these results demonstrate an emerging role for PBF in colorectal tumorigenesis through regulating p53 (show TP53 Proteins) activity, with implications for PBF as a prognostic indicator for invasive tumors.

  4. These findings indicate that miR (show MLXIP Proteins)-584 suppresses glioma cell growth by negatively regulating the expression of PTTG1IP, suggesting that miR (show MLXIP Proteins)-584 has a tumor suppressive role in human glioma pathogenesis.

  5. protooncogene PBF is a negative regulator of p53 (show TP53 Proteins) function in thyroid tumorigenesis, in which PBF is generally overexpressed and p53 (show TP53 Proteins) mutations are rare compared with other tumor types

  6. Data from mutant recombinant proteins suggest that proto-oncogene PBF is a phosphoprotein and highlight importance of tyrosine residue Y174 in both endocytosis of PBF and its interaction/co-localization with NIS/SLC5A5 (sodium-iodide symporter).

  7. PBF expression may be a promising biomarker for prognostic and therapeutic purposes in papillary thyroid carcinoma patients.

  8. Authors identified pituitary tumor-transforming gene 1 (PTTG1 (show PTTG1 Proteins)) binding factor (PBF) as a target of miR (show MLXIP Proteins)-122 and demonstrated that hepatitis B virus replication causes an obvious increase in PBF levels.

  9. The present study provides the first epidemiological evidence that functional regulatory variants of PTTG1IP were associated with the risk of ER-positive breast cancer, further supporting its relevance as one proto-oncogene (show RAB1A Proteins) in breast cancer.

  10. overexpression of PBF causes thyroid cell proliferation, macrofollicular lesions, and hyperplasia, as well as repression of the critical therapeutic route for radioiodide uptake

PTTG1IP Protein Profile

Protein Summary

The encoded protein, which directly binds to pituitary tumor-transforming gene 1 protein (PTTG1), facilitates the nuclear translocation of PTTG1 and potentiates the transcriptional activation of basic fibroblast growth factor by PTTG1. The gene product localizes to both the cytoplasm and nucleus. Its NLS is required for its own nuclear localization, the nuclear localization of PTTG1, and its interaction with PTTG1.

Alternative names and synonyms associated with PTTG1IP

  • pituitary tumor-transforming 1 interacting protein (Pttg1ip)
  • pituitary tumor-transforming 1 interacting protein (PTTG1IP)
  • pituitary tumor-transforming gene 1 protein-interacting protein-like (LOC100624320)
  • 1810010L20Rik protein
  • AI314311 protein
  • AU018448 protein
  • C21orf1 protein
  • C21orf3 protein
  • C79540 protein
  • PBF protein

Protein level used designations for PTTG1IP

PBF , PTTG-binding factor , pituitary tumor-transforming gene 1 protein-interacting protein , pituitary tumor-transforming gene protein-binding factor

GENE ID SPECIES
108705 Mus musculus
365548 Rattus norvegicus
754 Homo sapiens
100717897 Cavia porcellus
617245 Bos taurus
420545 Gallus gallus
100174140 Pongo abelii
100624320 Sus scrofa
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