CXCL5 Protein (AA 46-117, partial) (His tag)

Catalog No. ABIN1046743

Product Details

Target: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Protein Type: Recombinant

Protein Characteristics: AA 46-117, partial

Origin: Mouse

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CXCL5 protein is labelled with His tag.

Application: SDS-PAGE (SDS), ELISA

Sequence: IAATELRCVC LTVTPKINPK LIANLEVIPA GPQCPTVEVI AKLKNQKEVC LDPEAPVIKK IIQKILGSDK KK

Characteristics: May participate in the recruitment of inflammatory cells by injured or infected tissue. GCP-2(1-78) and, more potent, GCP-2(9-78) attract neutrophils and are involved in neutrophil activation.

Purity: 90 %

Application Details

Comment:

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 6M guanidine hydrochloride, 20mM Tris

Storage: -20 °C

References

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Wuyts, DHaese, Cremers, Menten, Lenaerts, De Loof, Heremans, Proost, Van Damme: "NH2- and COOH-terminal truncations of murine granulocyte chemotactic protein-2 augment the in vitro and in vivo neutrophil chemotactic potency." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 163, Issue 11, pp. 6155-63, (1999) (PubMed).

Wuyts, Haelens, Proost, Lenaerts, Conings, Opdenakker, Van Damme: "Identification of mouse granulocyte chemotactic protein-2 from fibroblasts and epithelial cells. Functional comparison with natural KC and macrophage inflammatory protein-2." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 157, Issue 4, pp. 1736-43, (1996) (PubMed).

Smith, Herschman: "Glucocorticoid-attenuated response genes encode intercellular mediators, including a new C-X-C chemokine." in: The Journal of biological chemistry, Vol. 270, Issue 28, pp. 16756-65, (1995) (PubMed).

Target Details

Target: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Alternative Name: C-X-C motif chemokine 5 (CXCL5 Products)

Synonyms: ENA-78 Protein, SCYB5 Protein, Cxcl6 Protein, CXCL5 Protein, GCP-2 Protein, GCP2 Protein, SCYB6 Protein, AMCF-II Protein, LIX Protein, Scyb5 Protein, Scyb6 Protein, C-X-C motif chemokine ligand 5 Protein, C-X-C motif chemokine ligand 6 Protein, chemokine (C-X-C motif) ligand 5 Protein, C-X-C motif chemokine 5 Protein, CXCL5 Protein, Cxcl6 Protein, LOC701946 Protein, LOC703222 Protein, Cxcl5 Protein

Background: Synonyms: Cytokine LIX Small-inducible cytokine B5

Molecular Weight: 11.9 kD

UniProt: P50228

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity