Carbonic Anhydrase IX (CA9) (AA 64-399), (partial) protein (GST tag)

Details for Product No. ABIN1046758
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Protein Name
Synonyms CA9, CAIX, Ca9, MN/CA9, MN
Protein Characteristics
AA 64-399, partial
Origin
Human
(9), (4)
Source
Escherichia coli (E. coli)
(9), (2), (1), (1)
Protein Type Recombinant
Purification tag / Conjugate
GST tag
Application
SDS-PAGE (SDS), ELISA
Pubmed 3 references available
Quantity 1 mg
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Catalog No. ABIN1046758
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Sequence DLPSEEDSPR EEDPPGEEDL PGEEDLPGEE DLPEVKPKSE EEGSLKLEDL PTVEAPGDPQ EPQNNAHRDK EGDDQSHWRY GGDPPWPRVS PACAGRFQSP VDIRPQLAAF CPALRPLELL GFQLPPLPEL RLRNNGHSVQ LTLPPGLEMA LGPGREYRAL QLHLHWGAAG RPGSEHTVEG HRFPAEIHVV HLSTAFARVD EALGRPGGLA VLAAFLEEGP EENSAYEQLL SRLEEIAEEG SETQVPGLDI SALLPSDFSR YFQYEGSLTT PPCAQGVIWT VFNQTVMLSA KQLHTLSDTL WGPGDSRLQL NFRATQPLNG RVIEASFPAG VDSSPR
Characteristics Reversible hydration of carbon dioxide. Participates in pH regulation. May be involved in the control of cell proliferation and transformation. Appears to be a novel specific biomarker for a cervical neoplasia.
Purity 90 %
Alternative Name Carbonic anhydrase 9
Background Synonyms: Carbonate dehydratase IX,Carbonic anhydrase IX,CA-IX,CAIX,Membrane antigen MN,P54/58N,Renal cell carcinoma-associated antigen G250,RCC-associated antigen G250,pMW1
Molecular Weight 64.2 kD
UniProt Q16790
Research Area Enzymes, Metabolism
Comment

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions For Research Use only
Buffer PBS buffer, 20mM GSH
Storage -20 °C
Product cited in: Pastorek, Pastoreková, Callebaut et al.: "Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment." in: Oncogene, Vol. 9, Issue 10, pp. 2877-88, 1994 (PubMed).

Grabmaier, Vissers, De Weijert et al.: "Molecular cloning and immunogenicity of renal cell carcinoma-associated antigen G250." in: International journal of cancer. Journal international du cancer, Vol. 85, Issue 6, pp. 865-70, 2000 (PubMed).

Humphray, Oliver, Hunt et al.: "DNA sequence and analysis of human chromosome 9." in: Nature, Vol. 429, Issue 6990, pp. 369-74, 2004 (PubMed).

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