You are viewing an incomplete version of our website. Please click to reload the website as full version.

LIM and SH3 Protein 1 (LASP1) (AA 1-243), (partial) protein (GST tag)

Details for Product No. ABIN1047340, Supplier: Login to see
Protein Name
  • lasp1
  • MGC53336
  • LASP1
  • MGC89667
  • Lasp-1
  • MLN50
  • AA408629
  • Def-4
  • SH3P6
  • Tg(Col1a1-lacZ)1Ngma
  • fb92f05
  • wu:fb92f05
  • zgc:77542
  • lasp-1
  • mln50
Protein Characteristics
AA 1-243, partial
Origin
Human
7
1
1
1
1
1
Source
Escherichia coli (E. coli)
6
4
1
1
Protein Type
Recombinant
Purification tag / Conjugate
GST tag
Application
SDS-PAGE (SDS), ELISA
Supplier
Login to see
Supplier Product No.
Login to see
Request

Showcase your results, aid the scientific community, and receive a full refund.

Contribute a validation

Learn more

Sequence MNPNCARCGK IVYPTEKVNC LDKFWHKACF HCETCKMTLN MKNYKGYEKK PYCNAHYPKQ SFTMVADTPE NLRLKQQSEL QSQVRYKEEF EKNKGKGFSV VADTPELQRI KKTQDQISNI KYHEEFEKSR MGPSGGEGME PERRDSQDGS SYRRPLEQQQ PHHIPTSAPV YQQPQQQPVA QSYGGYKEPA APVSIQRSAP GGGGKRYRAV YDYSAADEDE VSFQDGDTIV NVQQIDDGWM YGT
Characteristics Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types By similarity.
Purity 90 %
Background Synonyms: Metastatic lymph node gene 50 protein,MLN 50
Molecular Weight 55.2 kD
UniProt Q14847
Pathways
Comment

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Restrictions For Research Use only
Format Lyophilized
Buffer PBS buffer, 20mM GSH
Storage -20 °C
Product cited in: Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Tomasetto, Moog-Lutz, Régnier et al.: "Lasp-1 (MLN 50) defines a new LIM protein subfamily characterized by the association of LIM and SH3 domains." in: FEBS letters, Vol. 373, Issue 3, pp. 245-9, 1995 (PubMed).

Tomasetto, Régnier, Moog-Lutz et al.: "Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17." in: Genomics, Vol. 28, Issue 3, pp. 367-76, 1996 (PubMed).

Background publications Tao, Wollscheid, OBrien et al.: "Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry." in: Nature methods, Vol. 2, Issue 8, pp. 591-8, 2005 (PubMed).

Gevaert, Goethals, Martens et al.: "Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides." in: Nature biotechnology, Vol. 21, Issue 5, pp. 566-9, 2003 (PubMed).