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Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239), (partial) protein (GST tag)

Details for Product No. ABIN1047819, Supplier: Log in to see
Protein Name
  • CD258
  • HVEM-L
  • HVEML
  • LIGHT
  • LTg
  • Ly113
  • TNFSF14
  • TR2
Protein Characteristics
AA 1-239, partial
3
2
2
1
1
1
1
1
1
1
1
Origin
Human
13
5
2
Source
Escherichia coli (E. coli)
11
4
2
1
1
1
Protein Type
Recombinant
Purification tag / Conjugate
This TNFSF14 protein is labelled with GST tag.
Application
ELISA
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Sequence MEESVVRPSV FVVDGQTDIP FTRLGRSHRR QSCSVARVGL GLLLLLMGAG LAVQGWFLLQ LHWRLGEMVT RLPDGPAGSW EQLIQERRSH EVNPAAHLTG ANSSLTGSGG PLLWETQLGL AFLRGLSYHD GALVVTKAGY YYIYSKVQLG GVGCPLGLAS TITHGLYKRT PRYPEELELL VSQQSPCGRA TSSSRVWWDS SFLGGVVHLE AGEKVVVRVL DERLVRLRDG TRSYFGAFM
Characteristics Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.
Purity 90 %
Background Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.
Molecular Weight 53.6 kD
UniProt O43557
Comment

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions For Research Use only
Format Lyophilized
Concentration 0.2-2 mg/mL
Buffer Tris-based buffer, 50 % glycerol
Handling Advice Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week
Storage -20 °C
Storage Comment Store at -20 °C for extended storage, conserve at -20 °C or -80 °C
Supplier Images
SDS-PAGE (SDS) image for Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239), (partial) protein (GST tag) (ABIN1047819) Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14) (AA 1-239), (partial)...
Background publications Harrop, McDonnell, Brigham-Burke, Lyn, Minton, Tan, Dede, Spampanato, Silverman, Hensley, DiPrinzio, Emery, Deen, Eichman, Chabot-Fletcher, Truneh, Young: "Herpesvirus entry mediator ligand (HVEM-L), a novel ligand for HVEM/TR2, stimulates proliferation of T cells and inhibits HT29 cell growth." in: The Journal of biological chemistry, Vol. 273, Issue 42, pp. 27548-56, 1998 (PubMed).

Mauri, Ebner, Montgomery, Kochel, Cheung, Yu, Ruben, Murphy, Eisenberg, Cohen, Spear, Ware: "LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator." in: Immunity, Vol. 8, Issue 1, pp. 21-30, 1998 (PubMed).