WDR1 Protein (AA 189-461, partial) (GST tag)

Catalog No. ABIN1047937

Product Details

Target: WDR1 (WD Repeat Domain 1 (WDR1))

Protein Type: Recombinant

Protein Characteristics: AA 189-461, partial

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This WDR1 protein is labelled with GST tag.

Application: ELISA

Sequence: HKNGGKSYIY SGSHDGHINY WDSETGENDS FAGKGHTNQV SRMTVDESGQ LISCSMDDTV RYTSLMLRDY SGQGVVKLDV QPKCVAVGPG GYAVVVCIGQ IVLLKDQRKC FSIDNPGYEP EVVAVHPGGD TVAIGGVDGN VRLYSILGTT LKDEGKLLEA KGPVTDVAYS HDGAFLAVCD ASKVVTVFSV ADGYSENNVF YGHHAKIVCL AWSPDNEHFA SGGMDMMVYV WTLSDPETRV KIQDAHRLHH VSSLAWLDEH TLVTTSHDAS VKE

Characteristics: Please inquire if you are interested in this recombinant protein expressed in E. coli, mammalien cells or by baculovirus infection. Be aware about differences in price and lead time.

Purity: 90 %

Application Details

Comment:

The yeast protein expression system is the most economical and efficient eukaryotic system for secretion and intracellular expression. A protein expressed by the mammalian cell system is of very high-quality and close to the natural protein. But the low expression level, the high cost of medium and the culture conditions restrict the promotion of mammalian cell expression systems. The yeast protein expression system serve as a eukaryotic system integrate the advantages of the mammalian cell expression system. A protein expressed by yeast system could be modificated such as glycosylation, acylation, phosphorylation and so on to ensure the native protein conformation. It can be used to produce protein material with high added value that is very close to the natural protein. Our proteins produced by yeast expression system has been used as raw materials for downstream preparation of monoclonal antibodies.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: 0.2-2 mg/mL

Buffer: Tris-based buffer, 50 % glycerol

Handling Advice: Repeated freezing and thawing is not recommended. Store working aliquots at 4 °C for up to one week

Storage: -20 °C

Storage Comment: Store at -20 °C for extended storage, conserve at -20 °C or -80 °C

References

Gerhard, Wagner, Feingold, Shenmen, Grouse, Schuler, Klein, Old, Rasooly, Good, Guyer, Peck, Derge, Lipman, Collins, Jang, Sherry, Feolo, Misquitta, Lee, Rotmistrovsky, Greenhut, Schaefer, Buetow et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, (2004) (PubMed).

Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, (2003) (PubMed).

Adler, Winnicki, Gong, Lomax: "A gene upregulated in the acoustically damaged chick basilar papilla encodes a novel WD40 repeat protein." in: Genomics, Vol. 56, Issue 1, pp. 59-69, (1999) (PubMed).

Target Details

Target: WDR1 (WD Repeat Domain 1 (WDR1))

Alternative Name: WD repeat-containing protein 1 protein (WDR1 Products)

Synonyms: AIP1 Protein, NORI-1 Protein, Aip1 Protein, D5Wsu185e Protein, rede Protein, aip1 Protein, wdr1b Protein, wu:fa66e09 Protein, zgc:55793 Protein, zgc:77547 Protein, wdr1 Protein, wdr1-a Protein, wdr1-b Protein, wdr1a Protein, xAIP1-B Protein, WD repeat domain 1 Protein, WD repeat domain 1 L homeolog Protein, WD repeat domain 1 S homeolog Protein, WDR1 Protein, Wdr1 Protein, wdr1.L Protein, wdr1 Protein, wdr1.S Protein

Background: Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins By similarity.

Molecular Weight: 56.9 kD

UniProt: O75083

Pathways: Sensory Perception of Sound