LSM1 Protein (AA 1-133) (His tag)
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- Target See all LSM1 Proteins
- LSM1 (LSM1 Homolog, U6 Small Nuclear RNA Associated (LSM1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-133
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LSM1 protein is labelled with His tag.
- Purpose
- Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1/LSM1 (C-6His)
- Sequence
- MNYMPGTASL IEDIDKKHLV LLRDGRTLIG FLRSIDQFAN LVLHQTVERI HVGKKYGDIP RGIFVVRGEN VVLLGEIDLE KESDTPLQQV SIEEILEEQR VEQQTKLEAE KLKVQALKDR GLSIPRADTL DEYVEHHHHH H
- Characteristics
- Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1/LSM1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Tyr133) of Human LSM1 fused with a His tag at the C-terminus.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product LSM1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
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Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
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- Target
- LSM1 (LSM1 Homolog, U6 Small Nuclear RNA Associated (LSM1))
- Alternative Name
- Cancer-associated-Sm-like (LSM1 Products)
- Synonyms
- lsm1 Protein, NV45 Protein, CASM Protein, YJL124C Protein, 2810025O06Rik Protein, zgc:101136 Protein, LSM1 homolog, mRNA degradation associated Protein, LSM1 homolog, U6 small nuclear RNA associated Protein, LSM1 homolog, mRNA degradation associated L homeolog Protein, LSM1, U6 small nuclear RNA associated Protein, lsm1 Protein, Lsm1 Protein, lsm1.L Protein, LSM1 Protein
- Sub Type
- Fusionprotein
- Background
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U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6 snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer.
Alternative Names: U6 snRNA-Associated Sm-Like Protein LSm1, Cancer-Associated Sm-Like, Small Nuclear Ribonuclear CaSm, LSM1, CASM - Molecular Weight
- 16.23 kDa
- UniProt
- O15116
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