LSM1 Protein (His tag)
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- Target See all LSM1 Proteins
- LSM1 (LSM1 Homolog, U6 Small Nuclear RNA Associated (LSM1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This LSM1 protein is labelled with His tag.
- Purpose
- Recombinant Human LSM1 Protein (His Tag)
- Sequence
- Met 1-Tyr133
- Characteristics
- Recombinant Human U6 snRNA-Associated Sm-Like Protein LSm1 is produced by our E.coli expression system and the target gene encoding Met1-Tyr133 is expressed with a 6His tag at the C-terminus.
- Purity
- > 90 % as determined by reducing SDS-PAGE.
- Endotoxin Level
- < 1.0 EU per μg as determined by the LAL method.
- Top Product
- Discover our top product LSM1 Protein
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- LSM1 (LSM1 Homolog, U6 Small Nuclear RNA Associated (LSM1))
- Alternative Name
- LSM1 (LSM1 Products)
- Synonyms
- lsm1 Protein, NV45 Protein, CASM Protein, YJL124C Protein, 2810025O06Rik Protein, zgc:101136 Protein, LSM1 homolog, mRNA degradation associated Protein, LSM1 homolog, U6 small nuclear RNA associated Protein, LSM1 homolog, mRNA degradation associated L homeolog Protein, LSM1, U6 small nuclear RNA associated Protein, lsm1 Protein, Lsm1 Protein, lsm1.L Protein, LSM1 Protein
- Background
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Background: U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which plays an important role in pre-mRNA splicing. LSM1 binds specifically to the 3-terminal U-tract of U6snRNA. LSM1 can interact with SLBP when histone mRNA is being rapidly degraded during the S phase. In addition, LSM1 is associated with cellular transformation and the progression of several malignancies including mesothelioma, lung cancer and breast cancer.
Synonym: U6 snRNA-Associated Sm-Like Protein LSm1, Cancer-Associated Sm-Like, Small Nuclear Ribonuclear CaSm, LSM1, CASM
- Molecular Weight
- 16.2 kDa
- UniProt
- O15116
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