CXCL14 Protein
-
- Target See all CXCL14 Proteins
- CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))
- Protein Type
- Recombinant
- Biological Activity
- Active
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func)
- Purpose
- Recombinant Human C-X-C Motif Chemokine 14/CXCL14
- Sequence
- SKCKCSRKGP KIRYSDVKKL EMKPKYPHCE EKMVIITTKS VSRYRGQEHC LHPKLQSTKR FIKWYNAWNE KRRVYEE
- Characteristics
- Recombinant Human C-X-C Motif Chemokine Ligand 14/CXCL14 produced in E. coli is a single non-glycosylated polypeptide chain containing 77 amino acids with a molecular mass of 9.4 kDa.
- Purity
- > 95 % as determined by reducing SDS-PAGE.
- Sterility
- 0.2 μm filtered
- Endotoxin Level
- Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test
- Top Product
- Discover our top product CXCL14 Protein
-
-
- Comment
-
Biological activity: ED50 is 1.0-10.0 ng/ml as determined by the ability of Recombinant CXCL14 to induce calcium flux of prostaglandin E2 treated THP1 human acute monocytic leukemia cells.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
-
It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles. - Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 1M NaCl, pH 8.5.
- Handling Advice
- Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
- Storage
- 4 °C/-20 °C/-80 °C
- Storage Comment
-
Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months. - Expiry Date
- 3 months
-
- Target
- CXCL14 (Chemokine (C-X-C Motif) Ligand 14 (CXCL14))
- Alternative Name
- cxcl14 (CXCL14 Products)
- Synonyms
- BMAC Protein, BRAK Protein, KEC Protein, KS1 Protein, MIP-2g Protein, MIP2G Protein, NJAC Protein, SCYB14 Protein, 1110031L23Rik Protein, 1200006I23Rik Protein, AI414372 Protein, Kec Protein, MIP2gamma Protein, Scyb14 Protein, bolekine Protein, scyba Protein, fb67g04 Protein, wu:fb67g04 Protein, JSC Protein, bmac Protein, brak Protein, kec Protein, ks1 Protein, mip-2g Protein, mip2g Protein, njac Protein, scyb14 Protein, CXCL14 Protein, DKFZp469J175 Protein, C-X-C motif chemokine ligand 14 Protein, chemokine (C-X-C motif) ligand 14 Protein, chemokine (C-X-C motif) ligand 14 L homeolog Protein, CXCL14 Protein, Cxcl14 Protein, cxcl14 Protein, cxcl14.L Protein
- Background
-
Human Chemokine (C-X-C Motif) Ligand 14 (CXCL14) is constitutively expressed in certain normal tissues but is reduced or absent from many established tumor cell lines and human cancers. CXCL14 is known to be a chemoattractant for monocyte and dendritic cells. CXCL14 inhibits angiogenesis and exhibits antimicrobial activities. Mature human and mouse CXCL14 differ by only 2 amino acid residues.
Alternative Names: C-X-C Motif Chemokine 14, Chemokine BRAKm MIP-2G, Small-Inducible Cytokine B14, CXCL14, MIP2G, NJAC, SCYB14 - Molecular Weight
- 9.4 kDa
- UniProt
- O95715
- Pathways
- Autophagy
-