Fetuin A Protein (AA 119-367) (His tag)

Catalog No. ABIN1096642

Product Details

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Protein Type: Recombinant

Protein Characteristics: AA 119-367

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This Fetuin A protein is labelled with His tag.

Purpose: Recombinant Human Fetuin-A/AHSG/α-2-HS-Glycoprotein/AHSG (C-6His)

Sequence: APHGPGLIYR QPNCDDPETE EAALVAIDYI NQNLPWGYKH TLNQIDEVKV WPQQPSGELF EIEIDTLETT CHVLDPTPVA RCSVRQLKEH AVEGDCDFQL LKLDGKFSVV YAKCDSSPDS AEDVRKVCQD CPLLAPLNDT RVVHAAKAAL AAFNAQNNGS NFQLEEISRA QLVPLPPSTY VEFTVSGTDC VAKEATEAAK CNLLAEKQYG FCKATLSEKL GGAEVAVTCT VFQTQPVTSQ PQPEGANEAV PTPVVDPDAP PSPPLGAPGL PPAGSPPDSH VLLAAPPGHQ LHRAHYDLRH TFMGVVSLGS PSGEVSHPRK TRTVVQPSVG AAAGPVVPPC PGRIRHFKVV DHHHHHH

Characteristics: Recombinant Human alpha-2-HS-Glycoprotein/AHSG produced by transfected human cells is a secreted protein with sequence (Ala119-Val367) of Human AHSG fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 7.5.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Fetuin A (AHSG) (alpha-2-HS-Glycoprotein (AHSG))

Alternative Name: fetuin-a (AHSG Products)

Synonyms: ahs Protein, a2hs Protein, hsga Protein, fetua Protein, wu:fb63g02 Protein, zgc:103687 Protein, AHSG Protein, MGC116429 Protein, A2HS Protein, AHS Protein, FETUA Protein, HSGA Protein, Aa2-066 Protein, pp63 Protein, alpha-2-HS-glycoprotein Protein, alpha 2-HS glycoprotein Protein, alpha-2-HS-glycoprotein 1 Protein, alpha-2-HS-glycoprotein L homeolog Protein, Cphamn1_1981 Protein, AHSG Protein, ahsg Protein, ahsg1 Protein, ahsg.L Protein, Ahsg Protein

Sub Type: Fusionprotein

Background: Alpha-2-HS Glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. In addition, AHSG may influence the resolution of inflammation by modulating the phagocytosis of apoptotic cells by macrophages. ASHG blocks TGF-beta-dependent signaling in osteoblastic cells.
Alternative Names: Alpha-2-HS-Glycoprotein, Alpha-2-Z-Globulin, Ba-Alpha-2-Glycoprotein, Fetuin-A, AHSG, FETUA

Molecular Weight: 38.36 kDa

UniProt: P02765