GABARAPL1 Protein (AA 1-117) (His tag)

Catalog No. ABIN1096705

Product Details

Target: GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))

Protein Type: Recombinant

Protein Characteristics: AA 1-117

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This GABARAPL1 protein is labelled with His tag.

Purpose: Recombinant Human GABA Receptor-Associated Protein-Like 1/GABARAPL1 (N-6His)

Sequence: MGSSHHHHHH SSGLVPRGSH MKFQYKEDHP FEYRKKEGEK IRKKYPDRVP VIVEKAPKAR VPDLDKRKYL VPSDLTVGQF YFLIRKRIHL RPEDALFFFV NNTIPPTSAT MGQLYEDNHE EDYFLYVAYS DESVYGK

Characteristics: Recombinant Human gamma-Aminobutyric Acid Receptor-Associated Protein-Like 1/GABARAPL1 is produced by our E. coli expression system. The target protein is expressed with sequence (Met1-Lys117) of Human GABARAPL1 fused with a His tag at the N-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))

Alternative Name: GEC1 (GABARAPL1 Products)

Synonyms: gabarapl1 Protein, apg8l Protein, atg8 Protein, atg8l Protein, gec1 Protein, gabarapl1-a Protein, GABARAPL3 Protein, APG8-LIKE Protein, APG8L Protein, ATG8 Protein, ATG8B Protein, ATG8L Protein, GEC1 Protein, Gec1 Protein, 3110025G09Rik Protein, 9130422N19Rik Protein, AI196471 Protein, Apg8l Protein, Atg8l Protein, GECI Protein, GEC-1 Protein, GABA(A) receptor-associated protein like 1 Protein, GABA(A) receptor-associated protein like 1 S homeolog Protein, GABA type A receptor associated protein like 1 Protein, gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1 Protein, gabarapl1 Protein, gabarapl1.S Protein, GABARAPL1 Protein, Gabarapl1 Protein

Sub Type: Fusionprotein

Background: Gamma-Aminobutyric Acid Receptor-Associated Protein-Like 1 (GABARAPL1) is a cytoplasmic protein that belongs to the MAP1 LC3 family. GABARAPL1 is expressed at very high levels in the brain, heart, peripheral blood leukocytes, liver, kidney, placenta, and skeletal muscle. It can interact with GABRG2, OPRK1 and beta-Tubulin. GABARAPL1 increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor.
Alternative Names: Gamma-Aminobutyric Acid Receptor-Associated Protein-Like 1, Early Estrogen-Regulated Protein, GABA(A) Receptor-Associated Protein-Like 1, Glandular Epithelial Cell Protein 1, GEC-1, GABARAPL1, GEC1

Molecular Weight: 16.2 kDa

UniProt: Q9H0R8

Pathways: Autophagy