PLA2G16 Protein (AA 12-132) (His tag)

Catalog No. ABIN1097343

Product Details

Target: PLA2G16 (HRAS-Like Suppressor 3 (PLA2G16))

Protein Type: Recombinant

Protein Characteristics: AA 12-132

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This PLA2G16 protein is labelled with His tag.

Purpose: Recombinant Human Group XVI Phospholipase A1/A2/PLA2G16 (N-6His)

Sequence: MGSSHHHHHH SSGLVPRGSH MDLIEIFRPF YRHWAIYVGD GYVVHLAPPS EVAGAGAASV MSALTDKAIV KKELLYDVAG SDKYQVNNKH DDKYSPLPCS KIIQRAEELV GQEVLYKLTS ENCEHFVNEL RYGVARSDQV RD

Characteristics:

Recombinant Human Group XVI Phospholipase A1/A2/PLA2G16 (N-6His)

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, pH 8.0.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: -80 °C

Storage Comment: Store at < -20°C, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.

Expiry Date: 6 months

Target Details

Target: PLA2G16 (HRAS-Like Suppressor 3 (PLA2G16))

Alternative Name: PLA2G16 (PLA2G16 Products)

Synonyms: HRASLS3 Protein, HREV107 Protein, HRSL3 Protein, AdPLA Protein, H-REV107-1 Protein, HREV107-1 Protein, HREV107-3 Protein, C78643 Protein, Hrasls3 Protein, Hrev107 Protein, MLP-3 Protein, phospholipase A2 group XVI Protein, phospholipase A2, group XVI Protein, PLA2G16 Protein, Pla2g16 Protein

Background: Recombinant Human Group XVI Phospholipase A1/A2/PLA2G16 is produced by our E. coli expression system. The target protein is expressed with sequence (Asp12-Asp132) of Human PLA2G16 fused with a 6His tag at the N-terminus.
Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differentiation and survival. PLA2G16 regulates adipocyte lipolysis and release of fatty acids through a G-protein coupled pathway involving prostaglandin and EP3. It has also been reported to play a crucial role in the development of obesity in mouse models.

Molecular Weight: 15.93 kDa

UniProt: P53816

Pathways: Inositol Metabolic Process