OTC Protein (His tag)
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- Target See all OTC Proteins
- OTC (Ornithine Carbamoyltransferase (OTC))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This OTC protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Purification
- purified by chromatography
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product OTC Protein
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Ornithine Carbamoyltransferase (OTC) (AA 33-354) protein (His tag)
OTC Origin: Mouse Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Ornithine Carbamoyltransferase (OTC) (AA 33-354) protein (His tag)OTC Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Ornithine Carbamoyltransferase (OTC) (AA 1-99) protein (GST tag)OTC Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Ornithine Carbamoyltransferase (OTC) (AA 33-354) protein (His-SUMO Tag)OTC Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Ornithine Carbamoyltransferase (OTC) protein (DYKDDDDK Tag)OTC Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ornithine Carbamoyltransferase (OTC) (AA 33-354) protein (His-SUMO Tag)OTC Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Comment
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Synonyms: ornithine carbamoyltransferase, OCTD, OTCase
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/ml (determined by Bradford assay)
- Buffer
- 20 mM MES buffer (pH 6.0) containing 2 mM DTT, 10% glycerol, 100 mM NaCl
- Storage
- 4 °C
- Storage Comment
- Avoid repeated freezing and thawing cycles.
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- Target
- OTC (Ornithine Carbamoyltransferase (OTC))
- Alternative Name
- OTC (OTC Products)
- Synonyms
- OCTD Protein, 2810428A13Rik Protein, AA589422 Protein, AW457381 Protein, OCT Protein, Plxn2 Protein, mKIAA0463 Protein, F1B16.13 Protein, F1B16_13 Protein, ORNITHINE CARBAMOYLTRANSFERASE Protein, ornithine carbamoyltransferase Protein, BA4351 Protein, PSPTO4164 Protein, PLXN2 Protein, AI265390 Protein, Sf Protein, spf Protein, si:dkey-19h21.3 Protein, ornithine carbamoyltransferase Protein, plexin A2 Protein, ornithine carbamoyltransferase ArgF Protein, ornithine transcarbamylase Protein, OTC Protein, Plxna2 Protein, Otc Protein, argF Protein, argF-2 Protein, atpD-2 Protein, CNC04300 Protein, PLXNA2 Protein, otc Protein
- Background
- OTC, also called ornithine carbamoyltransferase, belongs to the ATCase/OTCase family. OTC plays a vital role in the urea cycle, catalyzing the second step in this pathway: the formation of L-citrulline from L-orthinine and carbamoyl phosphate. In humans, the urea cycle is an important pathway to detoxification of ammonia. Mutations in the gene encoding OTC are associated with the X-linked disorder OTCD (ornithine carbamoyltransferase deficiency). OTCD is a disorder of the urea cycle characterized by hyperammonemia. Recombinant human OTC protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 38.9kDa (347aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_000522
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